ty across the entire proteome, highlighting its most conserved peptide sequences (Fig. 4). Throughout the entire proteome, HLA-A and HLA-C alleles exhibited the relatively largest and smallest capacities to present SARS-CoV-2 antigens, respectively. However, each of the three major class I genes exhibited very similar patterns of peptide presentation across the proteome (Fig. S3). We additionally note that peptide presentation appea