PMC:7299399 / 31291-31831 JSONTXT

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All of these mechanisms may also occur simultaneously, enhancing the activity of immunosuppressive agents.\nConcerning the role of macrophages in COVID-19, the presence of ACE2-expressing CD68+CD169+ macrophages containing SARS-CoV-2 nucleoprotein antigen and showing an increased release of IL-6 was observed in infected spleen and lymph nodes.100 Notably, immunohistochemical and immunofluorescence analyses of lymph nodes and spleen tissue from autopsy samples of patients who died from COVID-19 revealed 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