ogy can offer to counter COVID-19 and similar pandemics. Nanotechnology Tools to Inactivate SARS-CoV-2 in Patients The main target of SARS-CoV-2 is the respiratory tract (upper airways, lung),36 although other organs might also be infected (e.g., gut, kidney) and vasculature21 also appears to be a prime target. The expression of ACE2 probably determines uptake by different tissues.37