Funding. This project was supported by the 2014 Government-funded Training Program for Talents in Clinical Medicine (3610037) and 2015 Government-funded Program for Talents in Clinical Medicine Training and Basic Research (81241037).

Supplementary Material
The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fnagi.2020.00137/full#supplementary-material.
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