PMC:7291971 / 11639-11845 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T237","span":{"begin":70,"end":77},"obj":"CHEBI:15377;CHEBI:15377"},{"id":"T238","span":{"begin":78,"end":86},"obj":"CHEBI:75958;CHEBI:75958"},{"id":"T239","span":{"begin":87,"end":91},"obj":"CHEBI:32145;CHEBI:32145"},{"id":"T240","span":{"begin":139,"end":152},"obj":"CHEBI:23447;CHEBI:23447"}],"text":"h, 72% for 5; 3 h, 28% for 6; 5.5 h, 60% for 7; 5.5 h for 8. (ii) 2 M aqueous solution LiOH, 0 °C, 0.5 h, 36% for 8.\nScheme 3 Synthesis of dinucleosides 10–13. (a) Ns-Cl, NEt3, DMF, 25 °C, 3.5 h, 40–72%; (b"}

{"project":"LitCovid-PubTator","denotations":[{"id":"115","span":{"begin":87,"end":91},"obj":"Chemical"},{"id":"124","span":{"begin":139,"end":152},"obj":"Chemical"},{"id":"125","span":{"begin":164,"end":166},"obj":"Chemical"},{"id":"126","span":{"begin":171,"end":175},"obj":"Chemical"},{"id":"127","span":{"begin":177,"end":180},"obj":"Chemical"}],"attributes":[{"id":"A125","pred":"tao:has_database_id","subj":"125","obj":"MESH:D009584"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"h, 72% for 5; 3 h, 28% for 6; 5.5 h, 60% for 7; 5.5 h for 8. (ii) 2 M aqueous solution LiOH, 0 °C, 0.5 h, 36% for 8.\nScheme 3 Synthesis of dinucleosides 10–13. (a) Ns-Cl, NEt3, DMF, 25 °C, 3.5 h, 40–72%; (b"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T32","span":{"begin":164,"end":166},"obj":"Disease"}],"attributes":[{"id":"A32","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0009735"}],"text":"h, 72% for 5; 3 h, 28% for 6; 5.5 h, 60% for 7; 5.5 h for 8. (ii) 2 M aqueous solution LiOH, 0 °C, 0.5 h, 36% for 8.\nScheme 3 Synthesis of dinucleosides 10–13. (a) Ns-Cl, NEt3, DMF, 25 °C, 3.5 h, 40–72%; (b"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T100","span":{"begin":16,"end":21},"obj":"http://purl.obolibrary.org/obo/CLO_0003588"},{"id":"T101","span":{"begin":106,"end":108},"obj":"http://purl.obolibrary.org/obo/CLO_0001313"},{"id":"T102","span":{"begin":161,"end":162},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T103","span":{"begin":167,"end":169},"obj":"http://purl.obolibrary.org/obo/CLO_0052906"},{"id":"T104","span":{"begin":205,"end":206},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"}],"text":"h, 72% for 5; 3 h, 28% for 6; 5.5 h, 60% for 7; 5.5 h for 8. (ii) 2 M aqueous solution LiOH, 0 °C, 0.5 h, 36% for 8.\nScheme 3 Synthesis of dinucleosides 10–13. (a) Ns-Cl, NEt3, DMF, 25 °C, 3.5 h, 40–72%; (b"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T183","span":{"begin":78,"end":86},"obj":"Chemical"},{"id":"T184","span":{"begin":87,"end":91},"obj":"Chemical"},{"id":"T185","span":{"begin":164,"end":166},"obj":"Chemical"},{"id":"T187","span":{"begin":167,"end":169},"obj":"Chemical"},{"id":"T188","span":{"begin":171,"end":175},"obj":"Chemical"},{"id":"T189","span":{"begin":177,"end":180},"obj":"Chemical"}],"attributes":[{"id":"A183","pred":"chebi_id","subj":"T183","obj":"http://purl.obolibrary.org/obo/CHEBI_75958"},{"id":"A184","pred":"chebi_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/CHEBI_33979"},{"id":"A185","pred":"chebi_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/CHEBI_33349"},{"id":"A186","pred":"chebi_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/CHEBI_33355"},{"id":"A187","pred":"chebi_id","subj":"T187","obj":"http://purl.obolibrary.org/obo/CHEBI_23116"},{"id":"A188","pred":"chebi_id","subj":"T188","obj":"http://purl.obolibrary.org/obo/CHEBI_35026"},{"id":"A189","pred":"chebi_id","subj":"T189","obj":"http://purl.obolibrary.org/obo/CHEBI_17741"}],"text":"h, 72% for 5; 3 h, 28% for 6; 5.5 h, 60% for 7; 5.5 h for 8. (ii) 2 M aqueous solution LiOH, 0 °C, 0.5 h, 36% for 8.\nScheme 3 Synthesis of dinucleosides 10–13. (a) Ns-Cl, NEt3, DMF, 25 °C, 3.5 h, 40–72%; (b"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T27","span":{"begin":126,"end":135},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"h, 72% for 5; 3 h, 28% for 6; 5.5 h, 60% for 7; 5.5 h for 8. (ii) 2 M aqueous solution LiOH, 0 °C, 0.5 h, 36% for 8.\nScheme 3 Synthesis of dinucleosides 10–13. (a) Ns-Cl, NEt3, DMF, 25 °C, 3.5 h, 40–72%; (b"}