PMC:7291971 / 1013-1311 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T18","span":{"begin":70,"end":79},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T19","span":{"begin":130,"end":142},"obj":"NCBITaxon:31032"},{"id":"T20","span":{"begin":146,"end":154},"obj":"SP_10"},{"id":"T21","span":{"begin":236,"end":244},"obj":"SP_10"},{"id":"T7397","span":{"begin":70,"end":79},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T53306","span":{"begin":130,"end":142},"obj":"NCBITaxon:31032"},{"id":"T48802","span":{"begin":146,"end":154},"obj":"SP_10"},{"id":"T86425","span":{"begin":236,"end":244},"obj":"SP_10"}],"text":"arious nitrogen-containing linkers. Unexpectedly, all the bisubstrate compounds were barely active against 2′-O MTases of several flaviviruses or SARS-CoV but surprisingly, seven of them showed efficient and specific inhibition against SARS-CoV N7-MTase (nsp14) in the micromolar to submicromolar r"}

{"project":"LitCovid-PubTator","denotations":[{"id":"12","span":{"begin":7,"end":15},"obj":"Chemical"}],"attributes":[{"id":"A12","pred":"tao:has_database_id","subj":"12","obj":"MESH:D009584"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"arious nitrogen-containing linkers. Unexpectedly, all the bisubstrate compounds were barely active against 2′-O MTases of several flaviviruses or SARS-CoV but surprisingly, seven of them showed efficient and specific inhibition against SARS-CoV N7-MTase (nsp14) in the micromolar to submicromolar r"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T4","span":{"begin":146,"end":154},"obj":"Disease"},{"id":"T5","span":{"begin":236,"end":244},"obj":"Disease"}],"attributes":[{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"arious nitrogen-containing linkers. Unexpectedly, all the bisubstrate compounds were barely active against 2′-O MTases of several flaviviruses or SARS-CoV but surprisingly, seven of them showed efficient and specific inhibition against SARS-CoV N7-MTase (nsp14) in the micromolar to submicromolar r"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T6","span":{"begin":92,"end":98},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"arious nitrogen-containing linkers. Unexpectedly, all the bisubstrate compounds were barely active against 2′-O MTases of several flaviviruses or SARS-CoV but surprisingly, seven of them showed efficient and specific inhibition against SARS-CoV N7-MTase (nsp14) in the micromolar to submicromolar r"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T12","span":{"begin":7,"end":15},"obj":"Chemical"}],"attributes":[{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_25555"}],"text":"arious nitrogen-containing linkers. Unexpectedly, all the bisubstrate compounds were barely active against 2′-O MTases of several flaviviruses or SARS-CoV but surprisingly, seven of them showed efficient and specific inhibition against SARS-CoV N7-MTase (nsp14) in the micromolar to submicromolar r"}