PMC:7289100 / 39418-39683 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T120","span":{"begin":78,"end":93},"obj":"Body_part"},{"id":"T121","span":{"begin":159,"end":165},"obj":"Body_part"}],"attributes":[{"id":"A120","pred":"fma_id","subj":"T120","obj":"http://purl.org/sig/ont/fma/fma67463"},{"id":"A121","pred":"fma_id","subj":"T121","obj":"http://purl.org/sig/ont/fma/fma84116"}],"text":"In vitro, both chloroquine and HCQ may block the transport of SARS-CoV-2 from early endosomes to endolysosomes, which may be required for release of the viral genome, and several studies have demonstrated in vitro activity of chloroquine against SARS-CoV [104,105]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T481","span":{"begin":62,"end":70},"obj":"Disease"},{"id":"T482","span":{"begin":62,"end":66},"obj":"Disease"},{"id":"T483","span":{"begin":246,"end":254},"obj":"Disease"},{"id":"T484","span":{"begin":246,"end":250},"obj":"Disease"}],"attributes":[{"id":"A481","pred":"mondo_id","subj":"T481","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A482","pred":"mondo_id","subj":"T482","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A483","pred":"mondo_id","subj":"T483","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A484","pred":"mondo_id","subj":"T484","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"In vitro, both chloroquine and HCQ may block the transport of SARS-CoV-2 from early endosomes to endolysosomes, which may be required for release of the viral genome, and several studies have demonstrated in vitro activity of chloroquine against SARS-CoV [104,105]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T290","span":{"begin":214,"end":222},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"In vitro, both chloroquine and HCQ may block the transport of SARS-CoV-2 from early endosomes to endolysosomes, which may be required for release of the viral genome, and several studies have demonstrated in vitro activity of chloroquine against SARS-CoV [104,105]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T159","span":{"begin":15,"end":26},"obj":"Chemical"},{"id":"T160","span":{"begin":226,"end":237},"obj":"Chemical"}],"attributes":[{"id":"A159","pred":"chebi_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A160","pred":"chebi_id","subj":"T160","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"In vitro, both chloroquine and HCQ may block the transport of SARS-CoV-2 from early endosomes to endolysosomes, which may be required for release of the viral genome, and several studies have demonstrated in vitro activity of chloroquine against SARS-CoV [104,105]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T18","span":{"begin":49,"end":58},"obj":"http://purl.obolibrary.org/obo/GO_0006810"}],"text":"In vitro, both chloroquine and HCQ may block the transport of SARS-CoV-2 from early endosomes to endolysosomes, which may be required for release of the viral genome, and several studies have demonstrated in vitro activity of chloroquine against SARS-CoV [104,105]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T242","span":{"begin":0,"end":265},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In vitro, both chloroquine and HCQ may block the transport of SARS-CoV-2 from early endosomes to endolysosomes, which may be required for release of the viral genome, and several studies have demonstrated in vitro activity of chloroquine against SARS-CoV [104,105]."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T531","span":{"begin":15,"end":26},"obj":"CHEBI:3638;DG_10;CHEBI:3638"},{"id":"T532","span":{"begin":62,"end":72},"obj":"SP_7"},{"id":"T533","span":{"begin":78,"end":93},"obj":"GO:0005769"},{"id":"T534","span":{"begin":97,"end":110},"obj":"GO:0036019"},{"id":"T535","span":{"begin":153,"end":158},"obj":"NCBITaxon:10239"},{"id":"T536","span":{"begin":159,"end":165},"obj":"SO:0001026"},{"id":"T537","span":{"begin":226,"end":237},"obj":"CHEBI:3638;DG_10;CHEBI:3638"},{"id":"T538","span":{"begin":246,"end":254},"obj":"SP_10"},{"id":"T19999","span":{"begin":15,"end":26},"obj":"CHEBI:3638;DG_10;CHEBI:3638"},{"id":"T25569","span":{"begin":62,"end":72},"obj":"SP_7"},{"id":"T16398","span":{"begin":78,"end":93},"obj":"GO:0005769"},{"id":"T23904","span":{"begin":97,"end":110},"obj":"GO:0036019"},{"id":"T1957","span":{"begin":153,"end":158},"obj":"NCBITaxon:10239"},{"id":"T97228","span":{"begin":159,"end":165},"obj":"SO:0001026"},{"id":"T4707","span":{"begin":226,"end":237},"obj":"CHEBI:3638;DG_10;CHEBI:3638"},{"id":"T70485","span":{"begin":246,"end":254},"obj":"SP_10"}],"text":"In vitro, both chloroquine and HCQ may block the transport of SARS-CoV-2 from early endosomes to endolysosomes, which may be required for release of the viral genome, and several studies have demonstrated in vitro activity of chloroquine against SARS-CoV [104,105]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1339","span":{"begin":62,"end":72},"obj":"Species"},{"id":"1340","span":{"begin":246,"end":254},"obj":"Species"},{"id":"1353","span":{"begin":15,"end":26},"obj":"Chemical"},{"id":"1354","span":{"begin":31,"end":34},"obj":"Chemical"},{"id":"1355","span":{"begin":226,"end":237},"obj":"Chemical"}],"attributes":[{"id":"A1339","pred":"tao:has_database_id","subj":"1339","obj":"Tax:2697049"},{"id":"A1340","pred":"tao:has_database_id","subj":"1340","obj":"Tax:694009"},{"id":"A1353","pred":"tao:has_database_id","subj":"1353","obj":"MESH:D002738"},{"id":"A1354","pred":"tao:has_database_id","subj":"1354","obj":"MESH:D006886"},{"id":"A1355","pred":"tao:has_database_id","subj":"1355","obj":"MESH:D002738"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In vitro, both chloroquine and HCQ may block the transport of SARS-CoV-2 from early endosomes to endolysosomes, which may be required for release of the viral genome, and several studies have demonstrated in vitro activity of chloroquine against SARS-CoV [104,105]."}

{"project":"2_test","denotations":[{"id":"32535093-32020029-4828884","span":{"begin":256,"end":259},"obj":"32020029"},{"id":"32535093-16115318-4828885","span":{"begin":260,"end":263},"obj":"16115318"}],"text":"In vitro, both chloroquine and HCQ may block the transport of SARS-CoV-2 from early endosomes to endolysosomes, which may be required for release of the viral genome, and several studies have demonstrated in vitro activity of chloroquine against SARS-CoV [104,105]."}