PMC:7283670 / 23200-24848 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T133","span":{"begin":57,"end":65},"obj":"Disease"},{"id":"T134","span":{"begin":134,"end":138},"obj":"Disease"},{"id":"T135","span":{"begin":939,"end":943},"obj":"Disease"},{"id":"T136","span":{"begin":1044,"end":1052},"obj":"Disease"},{"id":"T137","span":{"begin":1053,"end":1062},"obj":"Disease"},{"id":"T138","span":{"begin":1285,"end":1293},"obj":"Disease"},{"id":"T139","span":{"begin":1330,"end":1338},"obj":"Disease"}],"attributes":[{"id":"A133","pred":"mondo_id","subj":"T133","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A134","pred":"mondo_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A135","pred":"mondo_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A136","pred":"mondo_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A137","pred":"mondo_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A138","pred":"mondo_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A139","pred":"mondo_id","subj":"T139","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"4.1 Presumed asymptomatic carrier‐based transmission of COVID‐19\nInvestigation on a familial cluster of five patients concluded that SARS‐CoV‐2 might have actually been transmitted by an asymptomatic carrier in the family (Bai et al., 2020). Surprisingly, the first reverse transcription polymerase chain reaction (RT‐PCR) test of the asymptomatic family member was reported negative; a noteworthy example of a false‐negative result. Unwanted false‐negative results are inevitably reported due to a number of factors, for example, quality of the test kit, sufficiency of the collected sample, or performance of the test by clinicians. To this date, RT‐PCR has widely been used as a reliable diagnostic method (Corman et al., 2020). Thus, her second RT‐PCR result, reported positive, was unlikely to have been a false‐positive result; hence, it was accepted as the definite evidence that the suspected person had indeed been infected with SARS‐CoV‐2 (Bai et al., 2020).\nThere was also another study that reported an asymptomatic young boy with COVID‐19 infection. However, CT scans obtained from the subject exhibited abnormalities, indicative of an on‐going pulmonary pathology (Chan et al., 2020). If we presume that the findings regarding asymptomatic carrier‐based transmission of COVID‐19 can be replicated, this would prove COVID‐19 an overwhelmingly challenging issue to be controlled (Bai et al., 2020). The incubation period for the asymptomatic patient in the case of familial cluster was 19 days. Despite being a long period, it still perfectly falls in the suggested incubation period of 0–24 days (Bai et al., 2020; Guan et al., 2020)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T45951","span":{"begin":83,"end":84},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T63209","span":{"begin":324,"end":328},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T36718","span":{"begin":386,"end":387},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T31045","span":{"begin":410,"end":411},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T41328","span":{"begin":498,"end":499},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T19953","span":{"begin":547,"end":551},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T30116","span":{"begin":616,"end":620},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T58041","span":{"begin":657,"end":660},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T92301","span":{"begin":681,"end":682},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T28180","span":{"begin":810,"end":811},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T89176","span":{"begin":1522,"end":1523},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"4.1 Presumed asymptomatic carrier‐based transmission of COVID‐19\nInvestigation on a familial cluster of five patients concluded that SARS‐CoV‐2 might have actually been transmitted by an asymptomatic carrier in the family (Bai et al., 2020). Surprisingly, the first reverse transcription polymerase chain reaction (RT‐PCR) test of the asymptomatic family member was reported negative; a noteworthy example of a false‐negative result. Unwanted false‐negative results are inevitably reported due to a number of factors, for example, quality of the test kit, sufficiency of the collected sample, or performance of the test by clinicians. To this date, RT‐PCR has widely been used as a reliable diagnostic method (Corman et al., 2020). Thus, her second RT‐PCR result, reported positive, was unlikely to have been a false‐positive result; hence, it was accepted as the definite evidence that the suspected person had indeed been infected with SARS‐CoV‐2 (Bai et al., 2020).\nThere was also another study that reported an asymptomatic young boy with COVID‐19 infection. However, CT scans obtained from the subject exhibited abnormalities, indicative of an on‐going pulmonary pathology (Chan et al., 2020). If we presume that the findings regarding asymptomatic carrier‐based transmission of COVID‐19 can be replicated, this would prove COVID‐19 an overwhelmingly challenging issue to be controlled (Bai et al., 2020). The incubation period for the asymptomatic patient in the case of familial cluster was 19 days. Despite being a long period, it still perfectly falls in the suggested incubation period of 0–24 days (Bai et al., 2020; Guan et al., 2020)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T51","span":{"begin":27,"end":34},"obj":"Chemical"},{"id":"T52","span":{"begin":201,"end":208},"obj":"Chemical"},{"id":"T53","span":{"begin":1255,"end":1262},"obj":"Chemical"}],"attributes":[{"id":"A51","pred":"chebi_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/CHEBI_78059"},{"id":"A52","pred":"chebi_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_78059"},{"id":"A53","pred":"chebi_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/CHEBI_78059"}],"text":"4.1 Presumed asymptomatic carrier‐based transmission of COVID‐19\nInvestigation on a familial cluster of five patients concluded that SARS‐CoV‐2 might have actually been transmitted by an asymptomatic carrier in the family (Bai et al., 2020). Surprisingly, the first reverse transcription polymerase chain reaction (RT‐PCR) test of the asymptomatic family member was reported negative; a noteworthy example of a false‐negative result. Unwanted false‐negative results are inevitably reported due to a number of factors, for example, quality of the test kit, sufficiency of the collected sample, or performance of the test by clinicians. To this date, RT‐PCR has widely been used as a reliable diagnostic method (Corman et al., 2020). Thus, her second RT‐PCR result, reported positive, was unlikely to have been a false‐positive result; hence, it was accepted as the definite evidence that the suspected person had indeed been infected with SARS‐CoV‐2 (Bai et al., 2020).\nThere was also another study that reported an asymptomatic young boy with COVID‐19 infection. However, CT scans obtained from the subject exhibited abnormalities, indicative of an on‐going pulmonary pathology (Chan et al., 2020). If we presume that the findings regarding asymptomatic carrier‐based transmission of COVID‐19 can be replicated, this would prove COVID‐19 an overwhelmingly challenging issue to be controlled (Bai et al., 2020). The incubation period for the asymptomatic patient in the case of familial cluster was 19 days. Despite being a long period, it still perfectly falls in the suggested incubation period of 0–24 days (Bai et al., 2020; Guan et al., 2020)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T23985","span":{"begin":267,"end":288},"obj":"http://purl.obolibrary.org/obo/GO_0001171"},{"id":"T8492","span":{"begin":275,"end":288},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"text":"4.1 Presumed asymptomatic carrier‐based transmission of COVID‐19\nInvestigation on a familial cluster of five patients concluded that SARS‐CoV‐2 might have actually been transmitted by an asymptomatic carrier in the family (Bai et al., 2020). Surprisingly, the first reverse transcription polymerase chain reaction (RT‐PCR) test of the asymptomatic family member was reported negative; a noteworthy example of a false‐negative result. Unwanted false‐negative results are inevitably reported due to a number of factors, for example, quality of the test kit, sufficiency of the collected sample, or performance of the test by clinicians. To this date, RT‐PCR has widely been used as a reliable diagnostic method (Corman et al., 2020). Thus, her second RT‐PCR result, reported positive, was unlikely to have been a false‐positive result; hence, it was accepted as the definite evidence that the suspected person had indeed been infected with SARS‐CoV‐2 (Bai et al., 2020).\nThere was also another study that reported an asymptomatic young boy with COVID‐19 infection. However, CT scans obtained from the subject exhibited abnormalities, indicative of an on‐going pulmonary pathology (Chan et al., 2020). If we presume that the findings regarding asymptomatic carrier‐based transmission of COVID‐19 can be replicated, this would prove COVID‐19 an overwhelmingly challenging issue to be controlled (Bai et al., 2020). The incubation period for the asymptomatic patient in the case of familial cluster was 19 days. Despite being a long period, it still perfectly falls in the suggested incubation period of 0–24 days (Bai et al., 2020; Guan et al., 2020)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T179","span":{"begin":0,"end":65},"obj":"Sentence"},{"id":"T180","span":{"begin":66,"end":242},"obj":"Sentence"},{"id":"T181","span":{"begin":243,"end":434},"obj":"Sentence"},{"id":"T182","span":{"begin":435,"end":635},"obj":"Sentence"},{"id":"T183","span":{"begin":636,"end":732},"obj":"Sentence"},{"id":"T184","span":{"begin":733,"end":969},"obj":"Sentence"},{"id":"T185","span":{"begin":970,"end":1063},"obj":"Sentence"},{"id":"T186","span":{"begin":1064,"end":1199},"obj":"Sentence"},{"id":"T187","span":{"begin":1200,"end":1411},"obj":"Sentence"},{"id":"T188","span":{"begin":1412,"end":1507},"obj":"Sentence"},{"id":"T189","span":{"begin":1508,"end":1648},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"4.1 Presumed asymptomatic carrier‐based transmission of COVID‐19\nInvestigation on a familial cluster of five patients concluded that SARS‐CoV‐2 might have actually been transmitted by an asymptomatic carrier in the family (Bai et al., 2020). Surprisingly, the first reverse transcription polymerase chain reaction (RT‐PCR) test of the asymptomatic family member was reported negative; a noteworthy example of a false‐negative result. Unwanted false‐negative results are inevitably reported due to a number of factors, for example, quality of the test kit, sufficiency of the collected sample, or performance of the test by clinicians. To this date, RT‐PCR has widely been used as a reliable diagnostic method (Corman et al., 2020). Thus, her second RT‐PCR result, reported positive, was unlikely to have been a false‐positive result; hence, it was accepted as the definite evidence that the suspected person had indeed been infected with SARS‐CoV‐2 (Bai et al., 2020).\nThere was also another study that reported an asymptomatic young boy with COVID‐19 infection. However, CT scans obtained from the subject exhibited abnormalities, indicative of an on‐going pulmonary pathology (Chan et al., 2020). If we presume that the findings regarding asymptomatic carrier‐based transmission of COVID‐19 can be replicated, this would prove COVID‐19 an overwhelmingly challenging issue to be controlled (Bai et al., 2020). The incubation period for the asymptomatic patient in the case of familial cluster was 19 days. Despite being a long period, it still perfectly falls in the suggested incubation period of 0–24 days (Bai et al., 2020; Guan et al., 2020)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T39","span":{"begin":1556,"end":1561},"obj":"Phenotype"}],"attributes":[{"id":"A39","pred":"hp_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/HP_0002527"}],"text":"4.1 Presumed asymptomatic carrier‐based transmission of COVID‐19\nInvestigation on a familial cluster of five patients concluded that SARS‐CoV‐2 might have actually been transmitted by an asymptomatic carrier in the family (Bai et al., 2020). Surprisingly, the first reverse transcription polymerase chain reaction (RT‐PCR) test of the asymptomatic family member was reported negative; a noteworthy example of a false‐negative result. Unwanted false‐negative results are inevitably reported due to a number of factors, for example, quality of the test kit, sufficiency of the collected sample, or performance of the test by clinicians. To this date, RT‐PCR has widely been used as a reliable diagnostic method (Corman et al., 2020). Thus, her second RT‐PCR result, reported positive, was unlikely to have been a false‐positive result; hence, it was accepted as the definite evidence that the suspected person had indeed been infected with SARS‐CoV‐2 (Bai et al., 2020).\nThere was also another study that reported an asymptomatic young boy with COVID‐19 infection. However, CT scans obtained from the subject exhibited abnormalities, indicative of an on‐going pulmonary pathology (Chan et al., 2020). If we presume that the findings regarding asymptomatic carrier‐based transmission of COVID‐19 can be replicated, this would prove COVID‐19 an overwhelmingly challenging issue to be controlled (Bai et al., 2020). The incubation period for the asymptomatic patient in the case of familial cluster was 19 days. Despite being a long period, it still perfectly falls in the suggested incubation period of 0–24 days (Bai et al., 2020; Guan et al., 2020)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"553","span":{"begin":57,"end":65},"obj":"Disease"},{"id":"558","span":{"begin":110,"end":118},"obj":"Species"},{"id":"559","span":{"begin":134,"end":144},"obj":"Species"},{"id":"560","span":{"begin":939,"end":949},"obj":"Species"},{"id":"561","span":{"begin":925,"end":933},"obj":"Disease"},{"id":"568","span":{"begin":1035,"end":1038},"obj":"Species"},{"id":"569","span":{"begin":1455,"end":1462},"obj":"Species"},{"id":"570","span":{"begin":1044,"end":1052},"obj":"Disease"},{"id":"571","span":{"begin":1053,"end":1062},"obj":"Disease"},{"id":"572","span":{"begin":1285,"end":1293},"obj":"Disease"},{"id":"573","span":{"begin":1330,"end":1338},"obj":"Disease"}],"attributes":[{"id":"A553","pred":"tao:has_database_id","subj":"553","obj":"MESH:C000657245"},{"id":"A558","pred":"tao:has_database_id","subj":"558","obj":"Tax:9606"},{"id":"A559","pred":"tao:has_database_id","subj":"559","obj":"Tax:2697049"},{"id":"A560","pred":"tao:has_database_id","subj":"560","obj":"Tax:2697049"},{"id":"A561","pred":"tao:has_database_id","subj":"561","obj":"MESH:D007239"},{"id":"A568","pred":"tao:has_database_id","subj":"568","obj":"Tax:9606"},{"id":"A569","pred":"tao:has_database_id","subj":"569","obj":"Tax:9606"},{"id":"A570","pred":"tao:has_database_id","subj":"570","obj":"MESH:C000657245"},{"id":"A571","pred":"tao:has_database_id","subj":"571","obj":"MESH:D007239"},{"id":"A572","pred":"tao:has_database_id","subj":"572","obj":"MESH:C000657245"},{"id":"A573","pred":"tao:has_database_id","subj":"573","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"4.1 Presumed asymptomatic carrier‐based transmission of COVID‐19\nInvestigation on a familial cluster of five patients concluded that SARS‐CoV‐2 might have actually been transmitted by an asymptomatic carrier in the family (Bai et al., 2020). Surprisingly, the first reverse transcription polymerase chain reaction (RT‐PCR) test of the asymptomatic family member was reported negative; a noteworthy example of a false‐negative result. Unwanted false‐negative results are inevitably reported due to a number of factors, for example, quality of the test kit, sufficiency of the collected sample, or performance of the test by clinicians. To this date, RT‐PCR has widely been used as a reliable diagnostic method (Corman et al., 2020). Thus, her second RT‐PCR result, reported positive, was unlikely to have been a false‐positive result; hence, it was accepted as the definite evidence that the suspected person had indeed been infected with SARS‐CoV‐2 (Bai et al., 2020).\nThere was also another study that reported an asymptomatic young boy with COVID‐19 infection. However, CT scans obtained from the subject exhibited abnormalities, indicative of an on‐going pulmonary pathology (Chan et al., 2020). If we presume that the findings regarding asymptomatic carrier‐based transmission of COVID‐19 can be replicated, this would prove COVID‐19 an overwhelmingly challenging issue to be controlled (Bai et al., 2020). The incubation period for the asymptomatic patient in the case of familial cluster was 19 days. Despite being a long period, it still perfectly falls in the suggested incubation period of 0–24 days (Bai et al., 2020; Guan et al., 2020)."}