In summary, IAV was first isolated from a swine in USA in 1930 [34,349] and later antibodies for the human influenza viruses were reported in swine at the State Prison of New Jersey in 1937 [259]. More IAV outbreaks and cases in swine in North America were reported during 1981–2000; the frequency has now dramatically fallen in the last two decades (Figure 8). This might be due to improved swine influenza surveillance and vaccination in North America in recent decades. The H1N1, H1N2, H3N2, and A(H1N1)pdm09 viruses were reported from the commercial, backyard, exhibition, feral swine and wild boars in the United States.