The first complete genome sequence of IDV in Italian swine was retrieved from a symptomatic sow in 2015 which was identified to be closely related to the IDV sequence reported in Oklahoma swine in 2011 [217]. Further IDV prevalence in Italian swine was reported when 14, three and four swine were found positive for IDV antibodies in Veneto, Emilia Romagna and Lombardia regions, respectively during June 2015–May 2016. As a result, swine clinical samples collected during 2013–2014 were investigated retrospectively for IDV prevalence but were reported negative. An extended serological investigation detected IDV antibodies in 364 swine sera samples collected during 2015. These findings suggested that IDV was in circulation in Italian swine population only after 2014 [45].