The events of reverse zoonoses were suggested after the detection of A(H1N1)pdm09 virus seroprevalence in Vietnamese swine during October 2009–March 2010 [160]. One more evidence of reverse zoonosis was identified during February–March 2010 after six triple-reassortant H3N2 viruses having a novel cluster of the Triple Reassortant Internal Gene (TRIG) cassette were isolated. The HA and NA genes of these reassortant H3N2 isolates originated from human H3N2 viruses reported between 2004–2006 while the other six internal genes had a high similarity with the Korean and American isolates [161].