A molecular study reported the negative prevalence of avian-like H5N1 and H5N2 viruses in Egyptian swine in May 2008 [60] but the serological investigation identified H5N1 virus antibodies in seven and H5N2 virus antibodies in four swine sera samples [60] which suggested a past exposure of these swine to the viruses. The active H5N1 infection in Egyptian swine was again ruled out in October 2013 as the viral RNA could not be detected in 36 swine samples but interestingly, the antibodies against avian-like H5N1, H9N2, and A(H1N1)pdm09 viruses were detected in swine sera samples which suggested a past exposure [61]. Interestingly, 122 of the 157 swine nasal swab samples collected during 2014 and 2015 were found positive for IAV active infection using RT-PCR. As a result, HA subtyping identified 46 avian-origin H5N1, seven H9N2 and 69 A(H1N1)pdm09 viruses [61].