2.3. Ethical Approvals This systematic review did not involve animal sampling or experimental protocols in the laboratory. The data used for writing this article were obtained from the PubMed and Google Scholar databases. This systematic review is part of a research project which has already obtained the relevant ethical approvals from the Animal Research Ethics Committee (AREC), University of KwaZulu-Natal, Durban, South Africa; AREC Reference: AREC/041/019D. Additionally, the authors have the required permission to do research in terms of Section 20 of the Animal Diseases Act, 1984 (Act No. 35 of 1984) from the Department of Agriculture, Forestry and Fisheries (DAFF), Government of the Republic of South Africa; DAFF Reference: 12/11/1/5/4 (1425).