The second predicted sialic acid binding subsequence SSSGWTAGAAA has been of interest in the preceding Sections 1, 2, 3, 4, where it seemed a likely sugar binding site based on circumstantial evidence such as homologies to neurmaindiases and glycan esterases. Unfortunately, it lies in the range that generally disordered in experimental 3D structure, e.g. residues 246–262 in VVX (spike closed state) and 243–262 in VYB (spike open state). It also has modest maximum scores of 109, but the above considerations do not prohibit its potential importance.