Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Alessandro Casiraghi and Marco Domenicucci contributed equally to this work. Code availability Not applicable. Author contributions All the authors worked and are still working at the “Spedali Civili” Hospital in Brescia during the COVID-19 emergency. Alessandro Casiraghi, Fabio Albertini, Stefania Avanzini, Manuela Pansi Marini, and Pierangelo Guizzi coordinated the strategies for organizing the trauma hub. Alessandro Casiraghi, Marco Domenicucci, Stefano Cattaneo, and Giuseppe Milano had the idea for the article. Marco Domenicucci, Stefano Cattaneo, Emanuele Maggini, and Giuseppe Milano performed the literature search and data analysis. Marco Domenicucci, Stefano Cattaneo, Emanuele Maggini, Claudio Galante, and Giuseppe Milano wrote the article. Marco Domenicucci and Giuseppe Milano reviewed and edited the manuscript. Alessandro Casiraghi is the guarantor. Data availability Not applicable. Compliance with ethical standards Conflict of interest The authors declare that they have no conflict of interest. Ethics approval This manuscript does not involve humans, or human data, or animals, so it is not accompanied by a copy of the letter from the ethical committee. Consent to participate Not applicable. Consent for publication Not applicable.