2.2 Data collection We reviewed the hospital's electronic medical records, nurse records, laboratory findings, and imaging examinations for all patients with confirmed COVID-19. All data were checked by two researchers. We collected data on age, sex, body mass index, education levels, marital status, comorbidities (chronic respiratory disease, cardiovascular and cerebrovascular diseases, and gastrointestinal, endocrine, urologic, and nervous system diseases), current smoking status, time from symptom onset to admission, signs and symptoms at disease onset, chest imaging abnormalities (unilateral or bilateral distribution of patchy shadows or ground glass opacity), vital signs on admission (respiratory rate, percutaneous oxygen saturation, heart rate, systolic blood pressure, and body temperature), laboratory parameters within 24 h of admission (blood routine, blood biochemistry and electrolytes, cardiac biomarkers, and coagulation parameters), treatment (oxygen therapy, vasoconstrictive agents, antiviral therapy, antibiotics, corticosteroids, immunoglobulin, and immunoregulatory therapy), and complications during hospitalization (acute kidney injury (AKI), acute liver dysfunction, acute cardiac injury, hyperglycemia, and hospital-acquired infection (HAI)). AKI was identified based on the definition in the Kidney Disease: Improving Global Outcomes statement (KDIGO, 2012). Cardiac injury was diagnosed when the levels of serum hypersensitive cardiac troponin I exceeded the upper limit of normal (ULN), measured in the laboratory of the Wuhan Union Hospital. Acute liver dysfunction was defined as an ALT ≥ 1 × ULN. HAI was defined as infection acquired>48 h after hospital admission. For patient(s) with deterioration of the condition requiring ICU care, the subsequent data regarding laboratory parameters, treatment, and complications were not included in the final analysis.