Lactoferrin sources as supplements Product References Bovine and human milk Morinaga Industries in Japan (183) DoMO Food Ingredients, a subsidiary of Friesland Dairy Foods, in the Netherlands (184) Human recombinant lactoferrin Talactoferrin from Agennix, Inc., Houston, Texas, USA (184) Lactoferrin expression in transgenic rice Ventrus Biosciences, New York City, New York, USA (184) Transgenic cattle expressing human lactoferrin (185, 186) Transgenic maize Meristem therapeutics, Clermont-Ferrand, France (184) Lactoferrin supplementation in treatment of various diseases Might be useful in treating sepsis or necrotizing enterocolitis in preterm neonates (184) Support for vaginal health (187) LF may play a protective role in host defense against SARS-CoV infection through binding to HSPGs and blocking the preliminary interaction between SARS-CoV and host cells (cell culture study) (99) LF is a modulator of innate immune responses in the urinary tract and has potential application in novel therapeutic design for urinary tract infection (animal study) (188) Possible therapy against Candida albicans in the oral cavity (a hypothesis) (189) Protection against Chlamydia trachomatis (cell culture study) (190) Treatment of taste and smell abnormalities after chemotherapy (52) LF supplements and food with high levels of LF for oral health (99, 191) LF treatment of black stain associated with of iron metabolism disorders with lactoferrin (192) Aerosolized bovine LF counteracts infection, inflammation and iron dysbalance in a cystic fibrosis mouse model of Pseudomonas aeruginosa chronic lung infection (193) LF inhalations for lung health (194) LF for optimal skin moisture (195)