The current study provides evidence of behavioural changes and mental health concerns in response to the COVID-19 pandemic. Limitations include the use of a comparison group from a period six months past. However, the period of September 2019 was selected following analyses indicating it represented the “usual” patient profile (Titov et al., 2020 submitted for publication), and avoided the period immediately prior to March 2020 during which Australia experienced a severe bushfire crisis that disrupted the summer holiday period and affected the major cities. It is possible that the demographics and symptoms of the comparison and COVID-19 groups reported here differ for reasons unrelated to the COVID-19 crisis, although given the remarkably consistent characteristics of MindSpot users we believe that to be unlikely.