Table 4 Evaluation of the effect of QFPD on the robustness disturbance of COVID-19 network. Topology MXSG SGMH XCH WLS Others BXTM YDBF DTS 25.66 26.71 21.02 17.64 23.16 14.52 22.71 AC −4.63 −5.21 −3.02 −3.49 −5.38 −2.32 −3.78 APL 13.35 13.40 9.96 6.49 10.66 4.59 11.17 CoC −1.44 −1.64 −1.59 −1.30 −1.23 −1.15 −1.25 ClC −6.24 −6.46 −6.45 −6.36 −5.88 −6.46 −6.52 Average connectivity (AC), Connection centrality (CoC), Closeness centrality (ClC): the larger the quotient is, the more stable the network and, the less the influence made by the drug. Disturbance total score (DTS), Average length of shortest path (APL), : the larger the quotient is, the less stable the network and, the larger the influence made by the drug. Negative control formula: BXTM. Positive control formula: YDBF.