th the regulation of anti-viral, anti-inflammatory activity and metabolic programming. 1 Introduction 2019-novel coronavirus (2019-nCov) outbreak took place in December 2019 and continues to spread around the world. By April 3, 2020, more than 1 million patients have been diagnosed with corona virus disease 2019 (COVID-19) [1]. The virus has a long incubation period, is highly contagious, and is generally susceptible to all types of people, which has a huge negative impact on people's health, economic development, and social stability [2]. However, there is still a lack of effective clinical drugs or vaccine to control the virus. Traditional Chinese medicine has a good effect on viral infectious pneumonia and has shown a certain effect in the treatment of SARS. On February 7, 2020, the China Health Commission and the Administration of Traditional Chinese Medicine jointly issued a notice recommending formula Qingfei Paidu decoction (QFPD, Herba Ephedrae, Radix Glycyrrhizae, Semen Armeniacae Amarum, Gypsum Fibrosum, Ramulus Cinnamomi, Rhizoma Alismatis, Polyporus Umbellatus, Rhizoma Atractylodis Macrocephalae, Poria, Radix