Thirdly, the potential 96 target genes of WLS were analyzed by PPI network, and the results showed that there were 60 nodes and 143 edges. Only 1 modules score were > 2.5 (Fig. 5C). Module 1 (score: 2.706) consisted of 17 nodes and the seed gene was CNR2. KEGG pathway enrichment analysis showed that WLS modules were enriched in thyroid hormone signaling pathway, adipocytokine signaling pathway, neuroactive ligand-receptor interaction, et.al.