m, which uses the quantitative evaluation algorithm of multi-target drugs to disturb the disease network. Specifically, the disturbing effect of drugs on diseases is simulated by deleting disease network nodes. The disturbance rate of drugs is calculated by comparing the changes of network topology characteristics before and after drug intervention, which is used to evaluate the intervention effect of drugs on diseases. Firstly, COVID-19 disease network was constructed based on specific cytokines of COVID-19 [27] and differentially expressed genes of SARS (GSE36969, GSE51387, GSE68820). Then, this platform uses four kinds of network topology characteristics to evaluate the robustness of COVID-19 network, including network average connectivity, network average shortest path, connectivity centrality and compactness centrality. And the five formulae (MSXG, SGMH, XCH, WLS and Others) di