PMC:7247521 / 11581-12238 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"198","span":{"begin":49,"end":53},"obj":"Gene"},{"id":"199","span":{"begin":58,"end":63},"obj":"Gene"},{"id":"200","span":{"begin":191,"end":195},"obj":"Gene"},{"id":"201","span":{"begin":200,"end":205},"obj":"Gene"},{"id":"202","span":{"begin":423,"end":427},"obj":"Gene"},{"id":"203","span":{"begin":315,"end":324},"obj":"Disease"}],"attributes":[{"id":"A198","pred":"tao:has_database_id","subj":"198","obj":"Gene:59272"},{"id":"A199","pred":"tao:has_database_id","subj":"199","obj":"Gene:682"},{"id":"A200","pred":"tao:has_database_id","subj":"200","obj":"Gene:59272"},{"id":"A201","pred":"tao:has_database_id","subj":"201","obj":"Gene:682"},{"id":"A202","pred":"tao:has_database_id","subj":"202","obj":"Gene:59272"},{"id":"A203","pred":"tao:has_database_id","subj":"203","obj":"MESH:D011014"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T140","span":{"begin":18,"end":28},"obj":"GO:0010467"},{"id":"T141","span":{"begin":49,"end":53},"obj":"G_3;PG_10;PR:000003622"},{"id":"T142","span":{"begin":58,"end":63},"obj":"PR:000001324"},{"id":"T143","span":{"begin":71,"end":78},"obj":"UBERON:0000479"},{"id":"T144","span":{"begin":106,"end":113},"obj":"UBERON:0000479"},{"id":"T145","span":{"begin":171,"end":181},"obj":"GO:0010467"},{"id":"T146","span":{"begin":182,"end":187},"obj":"SO:0000704"},{"id":"T147","span":{"begin":191,"end":195},"obj":"G_3;PG_10;PR:000003622"},{"id":"T148","span":{"begin":200,"end":205},"obj":"PR:000001324"},{"id":"T149","span":{"begin":336,"end":341},"obj":"SO:0000704"},{"id":"T150","span":{"begin":403,"end":413},"obj":"GO:0010467"},{"id":"T151","span":{"begin":414,"end":419},"obj":"SO:0000704"},{"id":"T152","span":{"begin":423,"end":427},"obj":"G_3;PG_10;PR:000003622"},{"id":"T153","span":{"begin":431,"end":438},"obj":"UBERON:0001155;CL:0011108"},{"id":"T154","span":{"begin":439,"end":449},"obj":"CL:0011108;UBERON:0000483"},{"id":"T155","span":{"begin":450,"end":455},"obj":"CL:0011108"},{"id":"T156","span":{"begin":481,"end":485},"obj":"GO:0018995"}],"text":"To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T31","span":{"begin":71,"end":78},"obj":"Body_part"},{"id":"T32","span":{"begin":106,"end":113},"obj":"Body_part"},{"id":"T33","span":{"begin":439,"end":455},"obj":"Body_part"},{"id":"T34","span":{"begin":450,"end":455},"obj":"Body_part"},{"id":"T35","span":{"begin":486,"end":494},"obj":"Body_part"},{"id":"T36","span":{"begin":631,"end":639},"obj":"Body_part"}],"attributes":[{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T38","span":{"begin":315,"end":324},"obj":"Disease"}],"attributes":[{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"}],"text":"To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T88","span":{"begin":80,"end":81},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T89","span":{"begin":182,"end":187},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T90","span":{"begin":336,"end":341},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T91","span":{"begin":414,"end":419},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T92","span":{"begin":431,"end":438},"obj":"http://purl.obolibrary.org/obo/UBERON_0001155"},{"id":"T93","span":{"begin":439,"end":449},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T94","span":{"begin":450,"end":455},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T61","span":{"begin":486,"end":494},"obj":"Chemical"},{"id":"T62","span":{"begin":631,"end":639},"obj":"Chemical"}],"attributes":[{"id":"A61","pred":"chebi_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A62","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T10","span":{"begin":315,"end":324},"obj":"Phenotype"}],"attributes":[{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"LitCovid-sentences","denotations":[{"id":"T71","span":{"begin":0,"end":151},"obj":"Sentence"},{"id":"T72","span":{"begin":152,"end":246},"obj":"Sentence"},{"id":"T73","span":{"begin":247,"end":386},"obj":"Sentence"},{"id":"T74","span":{"begin":387,"end":530},"obj":"Sentence"},{"id":"T75","span":{"begin":531,"end":657},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}

{"project":"2_test","denotations":[{"id":"32554251-30462320-6393502","span":{"begin":147,"end":149},"obj":"30462320"}],"text":"To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P \u003c 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets."}