To understand the expression and distribution of ACE2 and CD147 across tissues, a radar plot including 53 tissues was performed through COXPRESdb [24]. And the top 200 co-expression genes of ACE2 and CD147 (P < 1E-16) were obtained, respectively. Then, text mining method from the literature was used to screen for pneumonia-associated genes through COREMINE (http://www.coremine.com/). In addition, co-expression genes of ACE2 in colonic epithelial cells [25] and HCoV-associated host proteins with references [26] were obtained. Finally, we performed UpsetView analysis (http://www.ehbio.com/ImageGP/) between these five sets of proteins and QFPD targets.