The stability and dynamics of the designed vaccine construct ensemble docked to innate immune receptors were disclosed through 100-ns of MD production run and interpreted through the root mean square deviation (RMSD) [81], root mean square fluctuation (RMSF) 82, the radius of gyration (Rg) [83] and beta factor (β-factor) [84] assays as depicted in Figure 10 .
Fig. 10 MD trajectories based calculation of Cα RMSD (top left), RMSD (top right), Rg (bottom left), and β-factor (bottom right).