t to virus evolution.

Graphical abstract

1  Introduction
A recent outbreak of pneumonia in Wuhan, China, is associated with Betacoronavirus of group 2B from family Coronaviridae and the order Nidovirales [1] [2]. The viruses are positive-sense RNA, enveloped and non-segmented [2]. This coronavirus disease (COVID-19) is known as a third human zoonosis of the 21st century and is caused by a new strain not previously identified in humans [1]. The coronaviruses causing minor infections of the respiratory tract in humans are NL63, OC43, hCoV-229E, and HKU1 while, the lethal coronavirus infections tha