Parameter Total (n = 33) Large hemorrhage with herniation (n = 5) Other hemorrhages (n = 28)
Supratherapeutic anti-factor Xa or PTT within 72 h prior to bleed 15 (45.5) 4 (80) 11 (39.3)
Anticoagulation prior to bleed*
 Therapeutic dose 22 (66.7) 5 (100.0) 17 (60.7)
 Unfractionated heparin, n 21 5 16
 Enoxaparin, n 4 0 4
 Argatroban, n 3 0 3
 Prophylactic dose 3 (9.1) 0 (0) 3 (10.7)
 Anticoagulation prior to admission 2 (6.1) 0 (0) 2 (7.1)
 None 6 (18.2) 0 (0) 6 (21.4)
Indication for Inpatient Anticoagulation
 Elevated D-dimer 18 (72.0) 3 (60.0) 15 (75.0)
 Thrombus 4 (16.0) 2 (40.0) 2 (10.0)
 Standard prophylaxis 3 (12.0) 0 (0) 3 (15.0)
Antiplatelet therapy prior to bleed
 None 22 (66.7) 3 (60) 19 (67.9)
 Aspirin alone 7 (21.2) 1 (20) 6 (21.4)
 Aspirin and clopidogrel 2 (6.1) 0 (0) 2 (7.1)
 Cilostazol alone 1 (3.0) 0 (0) 1 (3.6)
 Clopidogrel alone 1 (3.0) 1 (20) 0 (0.0)