ndergoes replication by using the host's machinery and synthesizes N, M, E, and S structural proteins. The negative strand of the RNA genome is produced using a positive-strand as a template. At the time of the process of replication in the host cell, the M protein attaches to the membranes of the endoplasmic reticulum, and the N protein binds to the genome. Nsp proteins help the RNA to assemble into a helical structure which enters the lumen of the endoplasmic reticulum. The viral progenies produced undergo exocytosis and enter the extracellular space [7].
Dr. TedrosAdhanom Ghebreyesus, Director-General of world health organization (WHO) on February 11, 2