Metabolic disorder related conditions, for example, hypertension, diabetes, obesity, and cardiovascular diseases, together with their inclining conditions, can be connected etiologically to the pathogenesis of MERS-CoV. These conditions act to decline the innate immune system of the host, thereby the inability of the host to fight against the pathogenesis of MERS-CoV. A study conducted on 637 MERS-CoV patients revealed that 15% of them have diabetes, 16% of them are obese, 50% of them had hypertension, and 30% are predisposed to cardiovascular diseases [65]. A 57-year-old diabetic and the hypertensive patient exhibited myocardial ischemia besides edema in the pulmonary tract, elevated troponin levels which returned to normal after 48 h, a chronic severe 3-vessel disease with no acute vessel closure characterized by coronary angiography. Later, he didn't respond and became hypotensive with facial paralysis on the left side [66].