The median duration of SARS-CoV-2 RNA shedding was 23 days (IQR 18–32 days). Only five patients (4.2%) had undetectable SARS-CoV-2 RNA within 10 days, 46 (38.3%) tested negative within 20 days, and 85 (70.8%) tested negative within 30 days from symptom onset. Most patients (86.7%) had undetectable SARS-CoV-2 RNA within 37 days after symptom onset, but a subgroup of 12 patients had detectable SARS-CoV-2 RNA up to 40 days after symptom onset (figure 1). The median duration of SARS-CoV-2 shedding did not differ significantly among the three groups with different disease severity (general 23 days versus severe 26 days versus critical 28 days; p=0.51).