Our findings suggest that there is an optimal climatic zone in which the concentration of SARS-CoV-2 markedly increases in the ambient environment (including the surfaces of objects). Even though the dispersal of the COVID-19 outbreak is affected by many countermeasures and medical conditions, our results confirm that there is an optimal temperature zone for the survival of SARS-CoV-2. The concentration of SARS-CoV-2 can markedly increase in the ambient environment including the surfaces of objects in this temperature range. It is worth recognizing that the spread of the COVID-19 outbreak is affected by several factors. In the present study, we investigated the natural factors affecting the COVID-19 pandemic. The analysis of large datasets (samples) yielded significant results with a high degree of confidence in the findings. These findings are important for the prediction of COVID-19 transmission in the near future. We cannot rely on the conjecture that COVID-19 outbreak will stop with increase in the temperature in summer. Undoubtedly, control strategies including school closure and social distancing have reduced the number of total cases considerably (Prem et al., 2020; Luo et al., 2020; Kissler et al., 2020).