the air in a designated hospital for COVID-19. • Environmental surface in medical areas was frequently contaminated. • Strict environmental surface disinfection and enhanced hand hygiene were recommended. Abstract Background Coronavirus disease 2019 (COVID-19) is characterized by risk of nosocomial transmission; however, the extent of environmental contamination and its potential contribution of environmental contamination to SARS-CoV-2 transmission are poorly understood. This study aimed to investigate whether environmental contamination may play a role in SARS-CoV-2 transmission. Methods Air samples were collected by natural precipitation, and environmental surface samples were collected by conventional sur