The positive rate of SARS-CoV-2 detection in the 200 surface samples was 19.00%. The positive rate in medical areas was higher than that in the living quarters, demonstrating the efficacy of the nosocomial infection prevention and control strategies. The wards were divided into different areas according to the risk level of infection, separating patients and healthcare workers using a physical barrier. Targeted measures for nosocomial infection prevention and control were carried out.