blished from China (Supplementary FigureĀ 2). The studies included mainly adults, although a few studies included a small proportion of pediatric patients. Two studies reported on outpatients only, whereas the remaining 55 studies reported on hospitalized patients or a combination of outpatients and hospitalized patients. Based on our inclusion strategy: 55 studies (96%) provided information on any GI symptom and 32 studies (56%) reported any data on liver abnormalitie