PMC:7212949 / 83492-84909 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T436","span":{"begin":1024,"end":1028},"obj":"Body_part"}],"attributes":[{"id":"A436","pred":"fma_id","subj":"T436","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"There are a few case reports and mini case series discussing the late trimester pregnancy and COVID-19. A study on 38 third trimester pregnant women did not show any severe pneumonia requiring mechanical ventilation or maternal deaths, despite co-morbid conditions. There were also no fetal or neonatal deaths.143 Another study (13 women in the second and third trimesters) reported 1 ARDS and septic shock case with a stillbirth at 34 weeks of gestation.144 Other reports on women with gestational ages of 25-39 weeks raise concern for an increased risk of preterm rupture of membranes and preterm delivery.144, 145, 146 However, in contrast, a retrospective study of 16 pregnant women infected with COVID-19 compared with 45 noninfected pregnant women showed no differences in preterm labor or preterm delivery, though the youngest gestational age included was only 35 weeks. Also, there was no difference in birth weight between the 2 groups.143 Pathophysiology in obstetric patients could be due to naturally suppressed cell-mediated immunity and physiologic respiratory changes.133 A noteworthy observation by Abbas et al has been an increasing incidence of hydatiform moles with the onset of the pandemic. The majority of these cases were primigravidae without other risk factors. They suggest an immune mediated mechanism triggered by the virus and recommend COVID testing in all women with hydatiform moles.65"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T689","span":{"begin":94,"end":102},"obj":"Disease"},{"id":"T690","span":{"begin":173,"end":182},"obj":"Disease"},{"id":"T691","span":{"begin":385,"end":389},"obj":"Disease"},{"id":"T692","span":{"begin":701,"end":709},"obj":"Disease"}],"attributes":[{"id":"A689","pred":"mondo_id","subj":"T689","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A690","pred":"mondo_id","subj":"T690","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A691","pred":"mondo_id","subj":"T691","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A692","pred":"mondo_id","subj":"T692","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"There are a few case reports and mini case series discussing the late trimester pregnancy and COVID-19. A study on 38 third trimester pregnant women did not show any severe pneumonia requiring mechanical ventilation or maternal deaths, despite co-morbid conditions. There were also no fetal or neonatal deaths.143 Another study (13 women in the second and third trimesters) reported 1 ARDS and septic shock case with a stillbirth at 34 weeks of gestation.144 Other reports on women with gestational ages of 25-39 weeks raise concern for an increased risk of preterm rupture of membranes and preterm delivery.144, 145, 146 However, in contrast, a retrospective study of 16 pregnant women infected with COVID-19 compared with 45 noninfected pregnant women showed no differences in preterm labor or preterm delivery, though the youngest gestational age included was only 35 weeks. Also, there was no difference in birth weight between the 2 groups.143 Pathophysiology in obstetric patients could be due to naturally suppressed cell-mediated immunity and physiologic respiratory changes.133 A noteworthy observation by Abbas et al has been an increasing incidence of hydatiform moles with the onset of the pandemic. The majority of these cases were primigravidae without other risk factors. They suggest an immune mediated mechanism triggered by the virus and recommend COVID testing in all women with hydatiform moles.65"}

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{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T107","span":{"begin":445,"end":454},"obj":"http://purl.obolibrary.org/obo/GO_0007565"},{"id":"T108","span":{"begin":487,"end":498},"obj":"http://purl.obolibrary.org/obo/GO_0007565"},{"id":"T109","span":{"begin":834,"end":845},"obj":"http://purl.obolibrary.org/obo/GO_0007565"},{"id":"T110","span":{"begin":1024,"end":1046},"obj":"http://purl.obolibrary.org/obo/GO_0002456"},{"id":"T111","span":{"begin":1024,"end":1046},"obj":"http://purl.obolibrary.org/obo/GO_0002449"}],"text":"There are a few case reports and mini case series discussing the late trimester pregnancy and COVID-19. A study on 38 third trimester pregnant women did not show any severe pneumonia requiring mechanical ventilation or maternal deaths, despite co-morbid conditions. There were also no fetal or neonatal deaths.143 Another study (13 women in the second and third trimesters) reported 1 ARDS and septic shock case with a stillbirth at 34 weeks of gestation.144 Other reports on women with gestational ages of 25-39 weeks raise concern for an increased risk of preterm rupture of membranes and preterm delivery.144, 145, 146 However, in contrast, a retrospective study of 16 pregnant women infected with COVID-19 compared with 45 noninfected pregnant women showed no differences in preterm labor or preterm delivery, though the youngest gestational age included was only 35 weeks. Also, there was no difference in birth weight between the 2 groups.143 Pathophysiology in obstetric patients could be due to naturally suppressed cell-mediated immunity and physiologic respiratory changes.133 A noteworthy observation by Abbas et al has been an increasing incidence of hydatiform moles with the onset of the pandemic. The majority of these cases were primigravidae without other risk factors. They suggest an immune mediated mechanism triggered by the virus and recommend COVID testing in all women with hydatiform moles.65"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T528","span":{"begin":173,"end":182},"obj":"Phenotype"},{"id":"T529","span":{"begin":401,"end":406},"obj":"Phenotype"},{"id":"T530","span":{"begin":591,"end":607},"obj":"Phenotype"},{"id":"T531","span":{"begin":796,"end":812},"obj":"Phenotype"}],"attributes":[{"id":"A528","pred":"hp_id","subj":"T528","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A529","pred":"hp_id","subj":"T529","obj":"http://purl.obolibrary.org/obo/HP_0031273"},{"id":"A530","pred":"hp_id","subj":"T530","obj":"http://purl.obolibrary.org/obo/HP_0001622"},{"id":"A531","pred":"hp_id","subj":"T531","obj":"http://purl.obolibrary.org/obo/HP_0001622"}],"text":"There are a few case reports and mini case series discussing the late trimester pregnancy and COVID-19. A study on 38 third trimester pregnant women did not show any severe pneumonia requiring mechanical ventilation or maternal deaths, despite co-morbid conditions. There were also no fetal or neonatal deaths.143 Another study (13 women in the second and third trimesters) reported 1 ARDS and septic shock case with a stillbirth at 34 weeks of gestation.144 Other reports on women with gestational ages of 25-39 weeks raise concern for an increased risk of preterm rupture of membranes and preterm delivery.144, 145, 146 However, in contrast, a retrospective study of 16 pregnant women infected with COVID-19 compared with 45 noninfected pregnant women showed no differences in preterm labor or preterm delivery, though the youngest gestational age included was only 35 weeks. Also, there was no difference in birth weight between the 2 groups.143 Pathophysiology in obstetric patients could be due to naturally suppressed cell-mediated immunity and physiologic respiratory changes.133 A noteworthy observation by Abbas et al has been an increasing incidence of hydatiform moles with the onset of the pandemic. The majority of these cases were primigravidae without other risk factors. They suggest an immune mediated mechanism triggered by the virus and recommend COVID testing in all women with hydatiform moles.65"}

{"project":"LitCovid-sentences","denotations":[{"id":"T855","span":{"begin":0,"end":103},"obj":"Sentence"},{"id":"T856","span":{"begin":104,"end":265},"obj":"Sentence"},{"id":"T857","span":{"begin":266,"end":877},"obj":"Sentence"},{"id":"T858","span":{"begin":878,"end":1211},"obj":"Sentence"},{"id":"T859","span":{"begin":1212,"end":1286},"obj":"Sentence"},{"id":"T860","span":{"begin":1287,"end":1417},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"There are a few case reports and mini case series discussing the late trimester pregnancy and COVID-19. A study on 38 third trimester pregnant women did not show any severe pneumonia requiring mechanical ventilation or maternal deaths, despite co-morbid conditions. There were also no fetal or neonatal deaths.143 Another study (13 women in the second and third trimesters) reported 1 ARDS and septic shock case with a stillbirth at 34 weeks of gestation.144 Other reports on women with gestational ages of 25-39 weeks raise concern for an increased risk of preterm rupture of membranes and preterm delivery.144, 145, 146 However, in contrast, a retrospective study of 16 pregnant women infected with COVID-19 compared with 45 noninfected pregnant women showed no differences in preterm labor or preterm delivery, though the youngest gestational age included was only 35 weeks. Also, there was no difference in birth weight between the 2 groups.143 Pathophysiology in obstetric patients could be due to naturally suppressed cell-mediated immunity and physiologic respiratory changes.133 A noteworthy observation by Abbas et al has been an increasing incidence of hydatiform moles with the onset of the pandemic. The majority of these cases were primigravidae without other risk factors. They suggest an immune mediated mechanism triggered by the virus and recommend COVID testing in all women with hydatiform moles.65"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T1766","span":{"begin":80,"end":89},"obj":"GO:0007565"},{"id":"T1767","span":{"begin":94,"end":102},"obj":"SP_7"},{"id":"T1768","span":{"begin":134,"end":142},"obj":"GO:0007565"},{"id":"T1769","span":{"begin":228,"end":234},"obj":"GO:0016265"},{"id":"T1770","span":{"begin":303,"end":309},"obj":"GO:0016265"},{"id":"T1771","span":{"begin":445,"end":454},"obj":"GO:0007565"},{"id":"T1772","span":{"begin":487,"end":498},"obj":"GO:0007565"},{"id":"T1773","span":{"begin":591,"end":607},"obj":"GO:0007567"},{"id":"T1774","span":{"begin":672,"end":680},"obj":"GO:0007565"},{"id":"T1775","span":{"begin":701,"end":709},"obj":"SP_7"},{"id":"T1776","span":{"begin":739,"end":747},"obj":"GO:0007565"},{"id":"T1777","span":{"begin":804,"end":812},"obj":"GO:0007567"},{"id":"T1778","span":{"begin":834,"end":845},"obj":"GO:0007565"},{"id":"T1779","span":{"begin":911,"end":916},"obj":"GO:0007567"},{"id":"T1780","span":{"begin":1063,"end":1074},"obj":"GO:0045333;UBERON:0001004"},{"id":"T1781","span":{"begin":1303,"end":1309},"obj":"UBERON:0002405"},{"id":"T1782","span":{"begin":1346,"end":1351},"obj":"NCBITaxon:10239"},{"id":"T74789","span":{"begin":80,"end":89},"obj":"GO:0007565"},{"id":"T28889","span":{"begin":94,"end":102},"obj":"SP_7"},{"id":"T24915","span":{"begin":134,"end":142},"obj":"GO:0007565"},{"id":"T4660","span":{"begin":228,"end":234},"obj":"GO:0016265"},{"id":"T96006","span":{"begin":303,"end":309},"obj":"GO:0016265"},{"id":"T95644","span":{"begin":445,"end":454},"obj":"GO:0007565"},{"id":"T53525","span":{"begin":487,"end":498},"obj":"GO:0007565"},{"id":"T64084","span":{"begin":591,"end":607},"obj":"GO:0007567"},{"id":"T30660","span":{"begin":672,"end":680},"obj":"GO:0007565"},{"id":"T91764","span":{"begin":701,"end":709},"obj":"SP_7"},{"id":"T91647","span":{"begin":739,"end":747},"obj":"GO:0007565"},{"id":"T76163","span":{"begin":804,"end":812},"obj":"GO:0007567"},{"id":"T73945","span":{"begin":834,"end":845},"obj":"GO:0007565"},{"id":"T70241","span":{"begin":911,"end":916},"obj":"GO:0007567"},{"id":"T62363","span":{"begin":1063,"end":1074},"obj":"GO:0045333;UBERON:0001004"},{"id":"T69412","span":{"begin":1303,"end":1309},"obj":"UBERON:0002405"},{"id":"T98851","span":{"begin":1346,"end":1351},"obj":"NCBITaxon:10239"}],"text":"There are a few case reports and mini case series discussing the late trimester pregnancy and COVID-19. A study on 38 third trimester pregnant women did not show any severe pneumonia requiring mechanical ventilation or maternal deaths, despite co-morbid conditions. There were also no fetal or neonatal deaths.143 Another study (13 women in the second and third trimesters) reported 1 ARDS and septic shock case with a stillbirth at 34 weeks of gestation.144 Other reports on women with gestational ages of 25-39 weeks raise concern for an increased risk of preterm rupture of membranes and preterm delivery.144, 145, 146 However, in contrast, a retrospective study of 16 pregnant women infected with COVID-19 compared with 45 noninfected pregnant women showed no differences in preterm labor or preterm delivery, though the youngest gestational age included was only 35 weeks. Also, there was no difference in birth weight between the 2 groups.143 Pathophysiology in obstetric patients could be due to naturally suppressed cell-mediated immunity and physiologic respiratory changes.133 A noteworthy observation by Abbas et al has been an increasing incidence of hydatiform moles with the onset of the pandemic. The majority of these cases were primigravidae without other risk factors. They suggest an immune mediated mechanism triggered by the virus and recommend COVID testing in all women with hydatiform moles.65"}

{"project":"LitCovid-PubTator","denotations":[{"id":"2021","span":{"begin":143,"end":148},"obj":"Species"},{"id":"2022","span":{"begin":332,"end":337},"obj":"Species"},{"id":"2023","span":{"begin":476,"end":481},"obj":"Species"},{"id":"2024","span":{"begin":681,"end":686},"obj":"Species"},{"id":"2025","span":{"begin":748,"end":753},"obj":"Species"},{"id":"2026","span":{"begin":978,"end":986},"obj":"Species"},{"id":"2027","span":{"begin":1387,"end":1392},"obj":"Species"},{"id":"2028","span":{"begin":94,"end":102},"obj":"Disease"},{"id":"2029","span":{"begin":173,"end":182},"obj":"Disease"},{"id":"2030","span":{"begin":228,"end":234},"obj":"Disease"},{"id":"2031","span":{"begin":294,"end":309},"obj":"Disease"},{"id":"2032","span":{"begin":385,"end":389},"obj":"Disease"},{"id":"2033","span":{"begin":394,"end":406},"obj":"Disease"},{"id":"2034","span":{"begin":419,"end":429},"obj":"Disease"},{"id":"2035","span":{"begin":558,"end":573},"obj":"Disease"},{"id":"2036","span":{"begin":687,"end":695},"obj":"Disease"},{"id":"2037","span":{"begin":701,"end":709},"obj":"Disease"},{"id":"2038","span":{"begin":779,"end":792},"obj":"Disease"},{"id":"2039","span":{"begin":1366,"end":1371},"obj":"Disease"}],"attributes":[{"id":"A2021","pred":"tao:has_database_id","subj":"2021","obj":"Tax:9606"},{"id":"A2022","pred":"tao:has_database_id","subj":"2022","obj":"Tax:9606"},{"id":"A2023","pred":"tao:has_database_id","subj":"2023","obj":"Tax:9606"},{"id":"A2024","pred":"tao:has_database_id","subj":"2024","obj":"Tax:9606"},{"id":"A2025","pred":"tao:has_database_id","subj":"2025","obj":"Tax:9606"},{"id":"A2026","pred":"tao:has_database_id","subj":"2026","obj":"Tax:9606"},{"id":"A2027","pred":"tao:has_database_id","subj":"2027","obj":"Tax:9606"},{"id":"A2028","pred":"tao:has_database_id","subj":"2028","obj":"MESH:C000657245"},{"id":"A2029","pred":"tao:has_database_id","subj":"2029","obj":"MESH:D011014"},{"id":"A2030","pred":"tao:has_database_id","subj":"2030","obj":"MESH:D003643"},{"id":"A2031","pred":"tao:has_database_id","subj":"2031","obj":"MESH:D066087"},{"id":"A2032","pred":"tao:has_database_id","subj":"2032","obj":"MESH:D012128"},{"id":"A2033","pred":"tao:has_database_id","subj":"2033","obj":"MESH:D012772"},{"id":"A2034","pred":"tao:has_database_id","subj":"2034","obj":"MESH:D050497"},{"id":"A2035","pred":"tao:has_database_id","subj":"2035","obj":"MESH:C563032"},{"id":"A2036","pred":"tao:has_database_id","subj":"2036","obj":"MESH:D007239"},{"id":"A2037","pred":"tao:has_database_id","subj":"2037","obj":"MESH:C000657245"},{"id":"A2038","pred":"tao:has_database_id","subj":"2038","obj":"MESH:D007752"},{"id":"A2039","pred":"tao:has_database_id","subj":"2039","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"There are a few case reports and mini case series discussing the late trimester pregnancy and COVID-19. A study on 38 third trimester pregnant women did not show any severe pneumonia requiring mechanical ventilation or maternal deaths, despite co-morbid conditions. There were also no fetal or neonatal deaths.143 Another study (13 women in the second and third trimesters) reported 1 ARDS and septic shock case with a stillbirth at 34 weeks of gestation.144 Other reports on women with gestational ages of 25-39 weeks raise concern for an increased risk of preterm rupture of membranes and preterm delivery.144, 145, 146 However, in contrast, a retrospective study of 16 pregnant women infected with COVID-19 compared with 45 noninfected pregnant women showed no differences in preterm labor or preterm delivery, though the youngest gestational age included was only 35 weeks. Also, there was no difference in birth weight between the 2 groups.143 Pathophysiology in obstetric patients could be due to naturally suppressed cell-mediated immunity and physiologic respiratory changes.133 A noteworthy observation by Abbas et al has been an increasing incidence of hydatiform moles with the onset of the pandemic. The majority of these cases were primigravidae without other risk factors. They suggest an immune mediated mechanism triggered by the virus and recommend COVID testing in all women with hydatiform moles.65"}

{"project":"2_test","denotations":[{"id":"32620220-32154135-2074263","span":{"begin":613,"end":616},"obj":"32154135"},{"id":"32620220-32151335-2074264","span":{"begin":618,"end":621},"obj":"32151335"},{"id":"32620220-15270922-2074265","span":{"begin":1083,"end":1086},"obj":"15270922"},{"id":"32620220-29414327-2074266","span":{"begin":1415,"end":1417},"obj":"29414327"}],"text":"There are a few case reports and mini case series discussing the late trimester pregnancy and COVID-19. A study on 38 third trimester pregnant women did not show any severe pneumonia requiring mechanical ventilation or maternal deaths, despite co-morbid conditions. There were also no fetal or neonatal deaths.143 Another study (13 women in the second and third trimesters) reported 1 ARDS and septic shock case with a stillbirth at 34 weeks of gestation.144 Other reports on women with gestational ages of 25-39 weeks raise concern for an increased risk of preterm rupture of membranes and preterm delivery.144, 145, 146 However, in contrast, a retrospective study of 16 pregnant women infected with COVID-19 compared with 45 noninfected pregnant women showed no differences in preterm labor or preterm delivery, though the youngest gestational age included was only 35 weeks. Also, there was no difference in birth weight between the 2 groups.143 Pathophysiology in obstetric patients could be due to naturally suppressed cell-mediated immunity and physiologic respiratory changes.133 A noteworthy observation by Abbas et al has been an increasing incidence of hydatiform moles with the onset of the pandemic. The majority of these cases were primigravidae without other risk factors. They suggest an immune mediated mechanism triggered by the virus and recommend COVID testing in all women with hydatiform moles.65"}