• Acute CVA (5.7%), impaired consciousness (14.8%), skeletal muscle injury (19.3%) more likely in severe disease (P < 0.05, P < 0.001)
• Patients with CNS symptoms more likely to have lower `lymphocyte and platelet counts and higher BUN (P < 0.05, P < 0.01, P < 0.05)
• Patients with muscle injury more likely to have higher neutrophils, CRP, D-dimer and lower lymphocyte count (P < 0.05, P < 0.001, P < 0.05, P < 0.01)
• Neurologic symptoms may be due to direct viral pathogenicity via hematogenous or retrograde neuronal spread, immunosuppression, or coagulation disorders