MERS-CoV
MERS-CoV causes both central and peripheral neurological abnormalities. Neurological symptoms occur later in the course of the illness as weakness and neuropathy and less frequently hypersomnolence and ataxia (Table 5).114 , 115 In a study of 4 patients with neurological symptoms conducted by Kim et al, MERS-CoV was not detected in the CSF, however, patients developed Guillain-Barre’ syndrome, Bickerstaff's encephalitis, critical illness myopathy, viral myopathy or toxin associated myopathy and neuropathy.114 Algahtani et al also report a case of cerebrovascular accident attributable to disseminated intravascular coagulation (DIC) and viral-induced autoimmune response.115 The authors are not aware of evidence describing the ocular manifestations of MERS-CoV or the ability to isolate the virus in tear samples.