Key findings on investigations CXR• Consolidation (78.3% at fever onset, eventually 100%)
• 54.6% unilateral, focal
• 45.4% multifocal or bilateral
• Peripheral zone predominant
CT• Progression of chest CT infiltrates 7-10 days after admission, resolution with treatment
• lll-defined peripheral GGO, usually subpleural • Leukopenia (2/3)
• Lymphopenia (2/3)
• CXR: Bilateral interstitial infiltrates • Abnormal CXR (59% on admission, 98% anytime)
• 63% patients – first unifocal infiltrates at 4.5 ± 2.1 days
• 37% patients - started as multifocal infiltrates at 5.8 ± 1.3 days after fever onset Initial CXR abnormal: 71%• One lung zone: 49%
• Multizonal: 21%
Chest CT abnormal (55% of 33)• One lobe: 55%
• Multilobar: 46%
• Focal ground-glass opacification: 24%
• Consolidation: 36%
• Both: 39%
Radiologic worsening in 80% at mean 7.4 days