Key study findings and message • Patients with hepatic dysfunction more likely to have moderate-high fever, more in males (P = 0.035, 0.005) • Abnormal liver function after admission associated with prolonged stay (P = 0.02) • Hepatic dysfunction more likely due to cholangiocyte damage by virus, not hepatocyte • Drug induced damage, SIRS may also play a role Cytokine storm possible associated with disease severity AST, ALT, T.bil, LDH higher in ICU patients (P < 0.001, P = 0.007,P = 0.02, P < 0.001)