PMC:7205724 / 26143-26665
Annnotations
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"935","span":{"begin":31,"end":60},"obj":"Gene"},{"id":"936","span":{"begin":62,"end":65},"obj":"Gene"},{"id":"937","span":{"begin":199,"end":203},"obj":"Gene"},{"id":"938","span":{"begin":205,"end":215},"obj":"Gene"},{"id":"939","span":{"begin":217,"end":223},"obj":"Gene"},{"id":"940","span":{"begin":229,"end":234},"obj":"Gene"},{"id":"941","span":{"begin":432,"end":438},"obj":"Gene"},{"id":"942","span":{"begin":443,"end":449},"obj":"Gene"},{"id":"943","span":{"begin":159,"end":163},"obj":"Species"},{"id":"944","span":{"begin":146,"end":158},"obj":"Disease"},{"id":"945","span":{"begin":267,"end":278},"obj":"Disease"},{"id":"946","span":{"begin":293,"end":305},"obj":"Disease"},{"id":"947","span":{"begin":500,"end":521},"obj":"Disease"}],"attributes":[{"id":"A935","pred":"tao:has_database_id","subj":"935","obj":"Gene:24310"},{"id":"A936","pred":"tao:has_database_id","subj":"936","obj":"Gene:24310"},{"id":"A937","pred":"tao:has_database_id","subj":"937","obj":"Gene:59272"},{"id":"A938","pred":"tao:has_database_id","subj":"938","obj":"Gene:999"},{"id":"A939","pred":"tao:has_database_id","subj":"939","obj":"Gene:5243"},{"id":"A940","pred":"tao:has_database_id","subj":"940","obj":"Gene:3394"},{"id":"A941","pred":"tao:has_database_id","subj":"941","obj":"Gene:3383"},{"id":"A942","pred":"tao:has_database_id","subj":"942","obj":"Gene:7412"},{"id":"A943","pred":"tao:has_database_id","subj":"943","obj":"Tax:10116"},{"id":"A944","pred":"tao:has_database_id","subj":"944","obj":"MESH:D006973"},{"id":"A945","pred":"tao:has_database_id","subj":"945","obj":"MESH:D006965"},{"id":"A946","pred":"tao:has_database_id","subj":"946","obj":"MESH:D007249"},{"id":"A947","pred":"tao:has_database_id","subj":"947","obj":"MESH:D007249"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T185","span":{"begin":128,"end":133},"obj":"Body_part"},{"id":"T186","span":{"begin":205,"end":215},"obj":"Body_part"},{"id":"T187","span":{"begin":341,"end":351},"obj":"Body_part"},{"id":"T188","span":{"begin":366,"end":370},"obj":"Body_part"},{"id":"T189","span":{"begin":432,"end":436},"obj":"Body_part"},{"id":"T190","span":{"begin":485,"end":495},"obj":"Body_part"}],"attributes":[{"id":"A185","pred":"fma_id","subj":"T185","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A186","pred":"fma_id","subj":"T186","obj":"http://purl.org/sig/ont/fma/fma61792"},{"id":"A187","pred":"fma_id","subj":"T187","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A188","pred":"fma_id","subj":"T188","obj":"http://purl.org/sig/ont/fma/fma9712"},{"id":"A189","pred":"fma_id","subj":"T189","obj":"http://purl.org/sig/ont/fma/fma67857"},{"id":"A190","pred":"fma_id","subj":"T190","obj":"http://purl.org/sig/ont/fma/fma62852"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-PD-UBERON
{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T27","span":{"begin":128,"end":133},"obj":"Body_part"},{"id":"T28","span":{"begin":366,"end":370},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T193","span":{"begin":267,"end":278},"obj":"Disease"},{"id":"T194","span":{"begin":293,"end":305},"obj":"Disease"},{"id":"T195","span":{"begin":509,"end":521},"obj":"Disease"}],"attributes":[{"id":"A193","pred":"mondo_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/MONDO_0005043"},{"id":"A194","pred":"mondo_id","subj":"T194","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A195","pred":"mondo_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T295","span":{"begin":78,"end":85},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T296","span":{"begin":106,"end":109},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T297","span":{"begin":128,"end":133},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T298","span":{"begin":128,"end":133},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T299","span":{"begin":207,"end":215},"obj":"http://purl.obolibrary.org/obo/PR_000001327"},{"id":"T300","span":{"begin":257,"end":265},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T216","span":{"begin":31,"end":42},"obj":"Chemical"},{"id":"T217","span":{"begin":78,"end":85},"obj":"Chemical"},{"id":"T218","span":{"begin":253,"end":256},"obj":"Chemical"},{"id":"T219","span":{"begin":415,"end":424},"obj":"Chemical"}],"attributes":[{"id":"A216","pred":"chebi_id","subj":"T216","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A217","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A218","pred":"chebi_id","subj":"T218","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A219","pred":"chebi_id","subj":"T219","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-MedDRA
{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T28","span":{"begin":31,"end":60},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T29","span":{"begin":62,"end":65},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A28","pred":"meddra_id","subj":"T28","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"},{"id":"A29","pred":"meddra_id","subj":"T29","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-PD-IDO
{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T123","span":{"begin":128,"end":133},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T124","span":{"begin":341,"end":351},"obj":"http://purl.obolibrary.org/obo/CL_0000738"},{"id":"T125","span":{"begin":485,"end":495},"obj":"http://purl.obolibrary.org/obo/CL_0000738"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-CHEBI
{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T136","span":{"begin":31,"end":42},"obj":"Chemical"},{"id":"T137","span":{"begin":78,"end":85},"obj":"Chemical"},{"id":"T138","span":{"begin":253,"end":256},"obj":"Chemical"}],"attributes":[{"id":"A138","pred":"chebi_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A136","pred":"chebi_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A137","pred":"chebi_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-PD-NCBITaxon
{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T237","span":{"begin":159,"end":163},"obj":"Species"}],"attributes":[{"id":"A237","pred":"ncbi_taxonomy_id","subj":"T237","obj":"NCBItxid:10118"},{"id":"A238","pred":"ncbi_taxonomy_id","subj":"T237","obj":"NCBItxid:10116"},{"id":"A239","pred":"ncbi_taxonomy_id","subj":"T237","obj":"NCBItxid:10114"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-sentences
{"project":"LitCovid-sample-sentences","denotations":[{"id":"T214","span":{"begin":0,"end":169},"obj":"Sentence"},{"id":"T215","span":{"begin":170,"end":352},"obj":"Sentence"},{"id":"T216","span":{"begin":353,"end":522},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-PD-UBERON
{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T27","span":{"begin":128,"end":133},"obj":"Body_part"},{"id":"T28","span":{"begin":366,"end":370},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-Pubtator
{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"935","span":{"begin":31,"end":60},"obj":"Gene"},{"id":"936","span":{"begin":62,"end":65},"obj":"Gene"},{"id":"944","span":{"begin":146,"end":158},"obj":"Disease"},{"id":"943","span":{"begin":159,"end":163},"obj":"Species"},{"id":"937","span":{"begin":199,"end":203},"obj":"Gene"},{"id":"938","span":{"begin":205,"end":215},"obj":"Gene"},{"id":"939","span":{"begin":217,"end":223},"obj":"Gene"},{"id":"940","span":{"begin":229,"end":234},"obj":"Gene"},{"id":"945","span":{"begin":267,"end":278},"obj":"Disease"},{"id":"946","span":{"begin":293,"end":305},"obj":"Disease"},{"id":"941","span":{"begin":432,"end":438},"obj":"Gene"},{"id":"942","span":{"begin":443,"end":449},"obj":"Gene"},{"id":"947","span":{"begin":500,"end":521},"obj":"Disease"}],"attributes":[{"id":"A938","pred":"pubann:denotes","subj":"938","obj":"Gene:999"},{"id":"A942","pred":"pubann:denotes","subj":"942","obj":"Gene:7412"},{"id":"A940","pred":"pubann:denotes","subj":"940","obj":"Gene:3394"},{"id":"A947","pred":"pubann:denotes","subj":"947","obj":"MESH:D007249"},{"id":"A935","pred":"pubann:denotes","subj":"935","obj":"Gene:24310"},{"id":"A943","pred":"pubann:denotes","subj":"943","obj":"Tax:10116"},{"id":"A941","pred":"pubann:denotes","subj":"941","obj":"Gene:3383"},{"id":"A944","pred":"pubann:denotes","subj":"944","obj":"MESH:D006973"},{"id":"A936","pred":"pubann:denotes","subj":"936","obj":"Gene:24310"},{"id":"A946","pred":"pubann:denotes","subj":"946","obj":"MESH:D007249"},{"id":"A937","pred":"pubann:denotes","subj":"937","obj":"Gene:59272"},{"id":"A945","pred":"pubann:denotes","subj":"945","obj":"MESH:D006965"},{"id":"A939","pred":"pubann:denotes","subj":"939","obj":"Gene:5243"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-UniProt
{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T2446","span":{"begin":4,"end":18},"obj":"Protein"},{"id":"T2449","span":{"begin":31,"end":60},"obj":"Protein"},{"id":"T2481","span":{"begin":62,"end":65},"obj":"Protein"},{"id":"T2506","span":{"begin":205,"end":215},"obj":"Protein"},{"id":"T2525","span":{"begin":229,"end":234},"obj":"Protein"},{"id":"T2529","span":{"begin":432,"end":438},"obj":"Protein"},{"id":"T2544","span":{"begin":443,"end":449},"obj":"Protein"}],"attributes":[{"id":"A2446","pred":"uniprot_id","subj":"T2446","obj":"https://www.uniprot.org/uniprot/P85895"},{"id":"A2447","pred":"uniprot_id","subj":"T2446","obj":"https://www.uniprot.org/uniprot/P56410"},{"id":"A2448","pred":"uniprot_id","subj":"T2446","obj":"https://www.uniprot.org/uniprot/P02789"},{"id":"A2449","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q9VJV3"},{"id":"A2450","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q9TX66"},{"id":"A2451","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q9NKE4"},{"id":"A2452","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q9GLN7"},{"id":"A2453","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q9GLN6"},{"id":"A2454","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q9EQM9"},{"id":"A2455","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q8CFN1"},{"id":"A2456","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q7TMC6"},{"id":"A2457","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q7M4L4"},{"id":"A2458","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q6Q4G4"},{"id":"A2459","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q6GTS2"},{"id":"A2460","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q59GY8"},{"id":"A2461","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q53YX9"},{"id":"A2462","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q50JE5"},{"id":"A2463","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q27572"},{"id":"A2464","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q10751"},{"id":"A2465","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q10715"},{"id":"A2466","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q10714"},{"id":"A2467","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/Q0GA41"},{"id":"A2468","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/P47820"},{"id":"A2469","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/P22968"},{"id":"A2470","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/P22967"},{"id":"A2471","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/P22966"},{"id":"A2472","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/P12822"},{"id":"A2473","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/P12821"},{"id":"A2474","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/P12820"},{"id":"A2475","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/P09470"},{"id":"A2476","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/O02852"},{"id":"A2477","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/E7EU16"},{"id":"A2478","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/B4DXI3"},{"id":"A2479","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/B0LPF0"},{"id":"A2480","pred":"uniprot_id","subj":"T2449","obj":"https://www.uniprot.org/uniprot/A4V0P3"},{"id":"A2481","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q9GLN7"},{"id":"A2482","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q9GLN6"},{"id":"A2483","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q9EQM9"},{"id":"A2484","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q8CFN1"},{"id":"A2485","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q7TMC6"},{"id":"A2486","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q7M4L4"},{"id":"A2487","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q6GTS2"},{"id":"A2488","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q59GY8"},{"id":"A2489","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q53YX9"},{"id":"A2490","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q50JE5"},{"id":"A2491","pred":"uniprot_id","subj":"T2481","obj":"https://www.uniprot.org/uniprot/Q10751"},{"id":"A2492","pred":"uniprot_id","subj":"T2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{"id":"A2544","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/Q6NUP8"},{"id":"A2545","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/Q63669"},{"id":"A2546","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/Q5FVS3"},{"id":"A2547","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/Q28260"},{"id":"A2548","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/P29534"},{"id":"A2549","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/P29533"},{"id":"A2550","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/P19320"},{"id":"A2551","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/E9PDD1"},{"id":"A2552","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/B4DKS4"},{"id":"A2553","pred":"uniprot_id","subj":"T2544","obj":"https://www.uniprot.org/uniprot/A8K6R7"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-Enju
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ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-PD-MAT
{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T10","span":{"begin":0,"end":3},"obj":"http://purl.obolibrary.org/obo/MAT_0000213"},{"id":"T11","span":{"begin":128,"end":133},"obj":"http://purl.obolibrary.org/obo/MAT_0000083"},{"id":"T12","span":{"begin":128,"end":133},"obj":"http://purl.obolibrary.org/obo/MAT_0000315"},{"id":"T13","span":{"begin":366,"end":370},"obj":"http://purl.obolibrary.org/obo/MAT_0000091"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-PD-GO-BP-0
{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T49","span":{"begin":185,"end":195},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T50","span":{"begin":293,"end":305},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T51","span":{"begin":327,"end":337},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T52","span":{"begin":384,"end":394},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T53","span":{"begin":509,"end":521},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-PD-FMA
{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T185","span":{"begin":128,"end":133},"obj":"Body_part"},{"id":"T186","span":{"begin":205,"end":215},"obj":"Body_part"},{"id":"T187","span":{"begin":341,"end":351},"obj":"Body_part"},{"id":"T188","span":{"begin":366,"end":370},"obj":"Body_part"},{"id":"T189","span":{"begin":432,"end":436},"obj":"Body_part"},{"id":"T190","span":{"begin":485,"end":495},"obj":"Body_part"}],"attributes":[{"id":"A185","pred":"fma_id","subj":"T185","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A187","pred":"fma_id","subj":"T187","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A188","pred":"fma_id","subj":"T188","obj":"http://purl.org/sig/ont/fma/fma9712"},{"id":"A186","pred":"fma_id","subj":"T186","obj":"http://purl.org/sig/ont/fma/fma61792"},{"id":"A190","pred":"fma_id","subj":"T190","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A189","pred":"fma_id","subj":"T189","obj":"http://purl.org/sig/ont/fma/fma67857"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-PD-MONDO
{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T183","span":{"begin":267,"end":278},"obj":"Disease"},{"id":"T184","span":{"begin":293,"end":305},"obj":"Disease"},{"id":"T185","span":{"begin":509,"end":521},"obj":"Disease"}],"attributes":[{"id":"A183","pred":"mondo_id","subj":"T183","obj":"http://purl.obolibrary.org/obo/MONDO_0005043"},{"id":"A184","pred":"mondo_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A185","pred":"mondo_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sample-GO-BP
{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T44","span":{"begin":185,"end":195},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T45","span":{"begin":293,"end":305},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T46","span":{"begin":327,"end":337},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T47","span":{"begin":384,"end":394},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T48","span":{"begin":509,"end":521},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-PD-GO-BP
{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T44","span":{"begin":185,"end":195},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T45","span":{"begin":293,"end":305},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T46","span":{"begin":327,"end":337},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T47","span":{"begin":384,"end":394},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T48","span":{"begin":509,"end":521},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T214","span":{"begin":0,"end":169},"obj":"Sentence"},{"id":"T215","span":{"begin":170,"end":352},"obj":"Sentence"},{"id":"T216","span":{"begin":353,"end":522},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}
2_test
{"project":"2_test","denotations":[{"id":"32413736-26016560-48112979","span":{"begin":165,"end":167},"obj":"26016560"},{"id":"T22851","span":{"begin":165,"end":167},"obj":"26016560"}],"text":"Egg ovotransferrin contains an angiotensin-converting enzyme (ACE) inhibitory peptide, known as IRW, that has shown to decrease blood pressure in hypertensive rats [33]. Through the up-regulation of ACE2, E-cadherin, ABCB-1, and IRF-8, IRW can decrease RAS activity, hyperplasia, and vascular inflammation and aid differential regulation of leukocytes. On the other hand, by the down-regulation of pro-inflammatory molecules, e.g., ICAM-1 and VCAM-1, IRW can reduce the recruitment of leukocytes and vascular inflammation."}