n at both 24 and 48 h after infection [25]. For SARS-CoV, such an effect was present at 24 h but absent at 48 h after infection [25]. The difference between SARS-CoV2 and SARS-CoV in response to type I IFN treatment may be due to differences in structural proteins of these viruses, including NSP3, ORF3b, and ORF6 [25].

6  Dev