PMC:7205724 / 17405-19470
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
599 | 90-95 | Species | denotes | human | Tax:9606 |
613 | 179-184 | Species | denotes | human | Tax:9606 |
614 | 369-383 | Species | denotes | Parvovirus B19 | Tax:10798 |
615 | 430-451 | Species | denotes | Clostridium difficile | Tax:1496 |
616 | 464-483 | Species | denotes | Mycobacterium avium | Tax:1764 |
617 | 485-511 | Species | denotes | Mycobacterium tuberculosis | Tax:1773 |
618 | 240-260 | Disease | denotes | autoimmune disorders | MESH:D001327 |
619 | 264-293 | Disease | denotes | primary antibody deficiencies | MESH:D000081207 |
620 | 361-367 | Disease | denotes | sepsis | MESH:D018805 |
621 | 384-393 | Disease | denotes | infection | MESH:D007239 |
622 | 405-423 | Disease | denotes | virus encephalitis | MESH:D004660 |
623 | 452-462 | Disease | denotes | infections | MESH:D007239 |
624 | 517-536 | Disease | denotes | Nocardia infections | MESH:D009617 |
625 | 552-562 | Disease | denotes | infections | MESH:D007239 |
633 | 663-672 | Species | denotes | 2019-nCoV | Tax:2697049 |
634 | 897-905 | Species | denotes | patients | Tax:9606 |
635 | 609-617 | Species | denotes | patients | Tax:9606 |
636 | 702-711 | Disease | denotes | infection | MESH:D007239 |
637 | 911-918 | Disease | denotes | COVID19 | MESH:C000657245 |
638 | 1037-1044 | Disease | denotes | COVID19 | MESH:C000657245 |
639 | 1128-1136 | Disease | denotes | COVID-19 | MESH:C000657245 |
642 | 1199-1207 | Species | denotes | patients | Tax:9606 |
643 | 1213-1221 | Disease | denotes | COVID-19 | MESH:C000657245 |
651 | 1250-1258 | Species | denotes | patients | Tax:9606 |
652 | 1628-1636 | Species | denotes | patients | Tax:9606 |
653 | 1362-1366 | Chemical | denotes | FIO2 | |
654 | 1377-1383 | Chemical | denotes | oxygen | MESH:D010100 |
655 | 1464-1482 | Chemical | denotes | methylprednisolone | MESH:D008775 |
656 | 1570-1588 | Chemical | denotes | methylprednisolone | MESH:D008775 |
657 | 1264-1272 | Disease | denotes | COVID-19 | MESH:C000657245 |
661 | 1812-1819 | Species | denotes | patient | Tax:9606 |
662 | 1869-1878 | Species | denotes | 2019-nCoV | Tax:2697049 |
663 | 2013-2021 | Species | denotes | patients | Tax:9606 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T134 | 17-32 | Body_part | denotes | immunoglobulins | http://purl.org/sig/ont/fma/fma62871 |
T135 | 272-280 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T136 | 425-428 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T137 | 736-741 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
T138 | 818-821 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T139 | 826-829 | Body_part | denotes | IgM | http://purl.org/sig/ont/fma/fma62873 |
T140 | 961-975 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
T141 | 1326-1336 | Body_part | denotes | lymphocyte | http://purl.org/sig/ont/fma/fma62863 |
T142 | 1497-1511 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
T143 | 1601-1615 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
T144 | 1862-1865 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T145 | 1956-1959 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T146 | 1964-1967 | Body_part | denotes | IgM | http://purl.org/sig/ont/fma/fma62873 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T20 | 736-741 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T123 | 240-260 | Disease | denotes | autoimmune disorders | http://purl.obolibrary.org/obo/MONDO_0007179 |
T124 | 264-293 | Disease | denotes | primary antibody deficiencies | http://purl.obolibrary.org/obo/MONDO_0015517 |
T125 | 384-393 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T126 | 405-423 | Disease | denotes | virus encephalitis | http://purl.obolibrary.org/obo/MONDO_0006009 |
T127 | 411-423 | Disease | denotes | encephalitis | http://purl.obolibrary.org/obo/MONDO_0019956 |
T128 | 430-462 | Disease | denotes | Clostridium difficile infections | http://purl.obolibrary.org/obo/MONDO_0000705 |
T129 | 499-511 | Disease | denotes | tuberculosis | http://purl.obolibrary.org/obo/MONDO_0018076 |
T130 | 517-536 | Disease | denotes | Nocardia infections | http://purl.obolibrary.org/obo/MONDO_0017776 |
T131 | 552-565 | Disease | denotes | infections in | http://purl.obolibrary.org/obo/MONDO_0005550 |
T132 | 566-597 | Disease | denotes | primary antibodies deficiencies | http://purl.obolibrary.org/obo/MONDO_0015517 |
T133 | 702-711 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T134 | 911-918 | Disease | denotes | COVID19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T135 | 1037-1044 | Disease | denotes | COVID19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T136 | 1128-1136 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T137 | 1213-1221 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T138 | 1264-1272 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T217 | 74-75 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T218 | 90-95 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T219 | 166-167 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T220 | 179-184 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T221 | 306-309 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T222 | 380-383 | http://purl.obolibrary.org/obo/CLO_0001798 | denotes | B19 |
T223 | 405-410 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T224 | 649-651 | http://purl.obolibrary.org/obo/CLO_0008192 | denotes | NP |
T225 | 719-721 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
T226 | 849-851 | http://purl.obolibrary.org/obo/CLO_0008192 | denotes | NP |
T227 | 855-857 | http://purl.obolibrary.org/obo/CLO_0001527 | denotes | 94 |
T228 | 887-889 | http://purl.obolibrary.org/obo/CLO_0001527 | denotes | 94 |
T229 | 1246-1249 | http://purl.obolibrary.org/obo/CLO_0050884 | denotes | ten |
T230 | 1421-1422 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T156 | 649-651 | Chemical | denotes | NP | http://purl.obolibrary.org/obo/CHEBI_50803|http://purl.obolibrary.org/obo/CHEBI_53793|http://purl.obolibrary.org/obo/CHEBI_73425 |
T159 | 849-851 | Chemical | denotes | NP | http://purl.obolibrary.org/obo/CHEBI_50803|http://purl.obolibrary.org/obo/CHEBI_53793|http://purl.obolibrary.org/obo/CHEBI_73425 |
T162 | 1377-1383 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T163 | 1448-1462 | Chemical | denotes | corticosteroid | http://purl.obolibrary.org/obo/CHEBI_50858 |
T164 | 1464-1482 | Chemical | denotes | methylprednisolone | http://purl.obolibrary.org/obo/CHEBI_6888 |
T165 | 1570-1588 | Chemical | denotes | methylprednisolone | http://purl.obolibrary.org/obo/CHEBI_6888 |
LitCovid-sample-MedDRA
Id | Subject | Object | Predicate | Lexical cue | meddra_id |
---|---|---|---|---|---|
T12 | 17-32 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | immunoglobulins | http://purl.bioontology.org/ontology/MEDDRA/10021496 |
T13 | 961-975 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | immunoglobulin | http://purl.bioontology.org/ontology/MEDDRA/10021496 |
T14 | 1326-1356 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | lymphocyte count and decreased | http://purl.bioontology.org/ontology/MEDDRA/10025256 |
T15 | 1357-1372 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | PaO2/FIO2 ratio | http://purl.bioontology.org/ontology/MEDDRA/10077710 |
T16 | 1377-1394 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | oxygen saturation | http://purl.bioontology.org/ontology/MEDDRA/10033316 |
T17 | 1497-1511 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | immunoglobulin | http://purl.bioontology.org/ontology/MEDDRA/10021496 |
T18 | 1601-1615 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | immunoglobulin | http://purl.bioontology.org/ontology/MEDDRA/10021496 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T70 | 185-193 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | diseases |
T71 | 251-260 | http://purl.obolibrary.org/obo/OGMS_0000045 | denotes | disorders |
T72 | 361-367 | http://purl.obolibrary.org/obo/IDO_0000636 | denotes | sepsis |
T73 | 384-393 | http://purl.obolibrary.org/obo/IDO_0000586 | denotes | infection |
T74 | 405-410 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T75 | 452-462 | http://purl.obolibrary.org/obo/IDO_0000586 | denotes | infections |
T76 | 526-536 | http://purl.obolibrary.org/obo/IDO_0000586 | denotes | infections |
T77 | 552-565 | http://purl.obolibrary.org/obo/IDO_0000586 | denotes | infections in |
T78 | 702-711 | http://purl.obolibrary.org/obo/IDO_0000586 | denotes | infection |
T79 | 782-789 | http://purl.obolibrary.org/obo/OGMS_0000020 | denotes | symptom |
T80 | 1300-1308 | http://purl.obolibrary.org/obo/OGMS_0000020 | denotes | symptoms |
T81 | 1740-1747 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | disease |
LitCovid-sample-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T103 | 1377-1383 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T104 | 1448-1462 | Chemical | denotes | corticosteroid | http://purl.obolibrary.org/obo/CHEBI_50858 |
T105 | 1464-1482 | Chemical | denotes | methylprednisolone | http://purl.obolibrary.org/obo/CHEBI_6888 |
T106 | 1570-1588 | Chemical | denotes | methylprednisolone | http://purl.obolibrary.org/obo/CHEBI_6888 |
T107 | 1862-1865 | Chemical | denotes | RNA | http://purl.obolibrary.org/obo/CHEBI_33697 |
LitCovid-sample-PD-NCBITaxon
Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
---|---|---|---|---|---|
T165 | 90-95 | Species | denotes | human | NCBItxid:9606 |
T166 | 179-184 | Species | denotes | human | NCBItxid:9606 |
T167 | 361-367 | Species | denotes | sepsis | NCBItxid:137507 |
T168 | 369-383 | Species | denotes | Parvovirus B19 | NCBItxid:10798 |
T169 | 395-410 | Species | denotes | West Nile virus | NCBItxid:11082 |
T170 | 425-428 | Species | denotes | HIV | NCBItxid:57667|NCBItxid:35274|NCBItxid:12721|NCBItxid:11709|NCBItxid:11676 |
T175 | 430-451 | Species | denotes | Clostridium difficile | NCBItxid:1496 |
T176 | 464-483 | Species | denotes | Mycobacterium avium | NCBItxid:1764 |
T177 | 485-511 | Species | denotes | Mycobacterium tuberculosis | NCBItxid:1773 |
T178 | 517-525 | Species | denotes | Nocardia | NCBItxid:1817 |
T179 | 663-672 | Species | denotes | 2019-nCoV | NCBItxid:2697049 |
T180 | 911-918 | Species | denotes | COVID19 | NCBItxid:2697049 |
T181 | 1037-1044 | Species | denotes | COVID19 | NCBItxid:2697049 |
T182 | 1128-1136 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T183 | 1213-1221 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T184 | 1264-1272 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T185 | 1869-1878 | Species | denotes | 2019-nCoV | NCBItxid:2697049 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T141 | 0-39 | Sentence | denotes | 4.2 Intravenous immunoglobulins (IVIG) |
T142 | 41-106 | Sentence | denotes | 4.2.1 Hypothesis: IVIG contains a large pool of human antibodies |
T143 | 107-294 | Sentence | denotes | IVIG is an immunomodulatory treatment currently useful for a variety of human diseases that share an idiopathic origin, ranging from autoimmune disorders to primary antibody deficiencies. |
T144 | 295-603 | Sentence | denotes | Also, IVIG has shown promising results in case of severe (such as sepsis, Parvovirus B19 infection, West Nile virus encephalitis, HIV, Clostridium difficile infections, Mycobacterium avium, Mycobacterium tuberculosis, and Nocardia infections) and recurrent infections in primary antibodies deficiencies [21]. |
T145 | 604-723 | Sentence | denotes | Most patients develop antibodies against the NP and RBD of 2019-nCoV during the second week after infection onset [22]. |
T146 | 724-919 | Sentence | denotes | Analysis of serum samples collected 14 or more days after symptom onset revealed detection of IgG and IgM antibodies against NP in 94% and 88% and RBD in 100% and 94% among patients with COVID19. |
T147 | 920-1045 | Sentence | denotes | Studies consistently show that increased immunoglobulin levels accompany the transition from early to late course of COVID19. |
T148 | 1046-1137 | Sentence | denotes | It poses the possibility that IVIG therapy might help to accelerate recovery from COVID-19. |
T149 | 1139-1221 | Sentence | denotes | 4.2.2 Rationale: IVIG might help to improve the outcome of patients with COVID-19 |
T150 | 1222-1521 | Sentence | denotes | The study [23] included ten patients with COVID-19 who demonstrated worsening symptoms, e.g., decreased lymphocyte count and decreased PaO2/FIO2 ratio and oxygen saturation, following treatment with a short-term moderate-dose corticosteroid (methylprednisolone 80 mg/d) plus immunoglobulin (10 g/d). |
T151 | 1522-1701 | Sentence | denotes | After switching to the double dose of 1600 mg/d methylprednisolone plus 20 g/d immunoglobulin, all of the patients improved in the clinical, laboratory, and paraclinical outcomes. |
T152 | 1702-1833 | Sentence | denotes | Passive immunization protects against disease, and so it should be administered as early as possible when the patient is diagnosed. |
T153 | 1834-2065 | Sentence | denotes | Studies show that the viral RNA of 2019-nCoV reaches its peak during the first week and then gradually decreases and that IgG and IgM begin to rise from the 10th day so that most patients have anti-viral antibodies by the 14th day. |
LitCovid-sample-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T20 | 736-741 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
---|---|---|---|---|---|
599 | 90-95 | Species | denotes | human | Tax:9606 |
613 | 179-184 | Species | denotes | human | Tax:9606 |
618 | 240-260 | Disease | denotes | autoimmune disorders | MESH:D001327 |
619 | 264-293 | Disease | denotes | primary antibody deficiencies | MESH:D000081207 |
620 | 361-367 | Disease | denotes | sepsis | MESH:D018805 |
614 | 369-383 | Species | denotes | Parvovirus B19 | Tax:10798 |
621 | 384-393 | Disease | denotes | infection | MESH:D007239 |
622 | 405-423 | Disease | denotes | virus encephalitis | MESH:D004660 |
615 | 430-451 | Species | denotes | Clostridium difficile | Tax:1496 |
623 | 452-462 | Disease | denotes | infections | MESH:D007239 |
616 | 464-483 | Species | denotes | Mycobacterium avium | Tax:1764 |
617 | 485-511 | Species | denotes | Mycobacterium tuberculosis | Tax:1773 |
624 | 517-536 | Disease | denotes | Nocardia infections | MESH:D009617 |
625 | 552-562 | Disease | denotes | infections | MESH:D007239 |
635 | 609-617 | Species | denotes | patients | Tax:9606 |
633 | 663-672 | Species | denotes | 2019-nCoV | Tax:2697049 |
636 | 702-711 | Disease | denotes | infection | MESH:D007239 |
634 | 897-905 | Species | denotes | patients | Tax:9606 |
637 | 911-918 | Disease | denotes | COVID19 | MESH:C000657245 |
638 | 1037-1044 | Disease | denotes | COVID19 | MESH:C000657245 |
639 | 1128-1136 | Disease | denotes | COVID-19 | MESH:C000657245 |
642 | 1199-1207 | Species | denotes | patients | Tax:9606 |
643 | 1213-1221 | Disease | denotes | COVID-19 | MESH:C000657245 |
651 | 1250-1258 | Species | denotes | patients | Tax:9606 |
657 | 1264-1272 | Disease | denotes | COVID-19 | MESH:C000657245 |
653 | 1362-1366 | Chemical | denotes | FIO2 | |
654 | 1377-1383 | Chemical | denotes | oxygen | MESH:D010100 |
655 | 1464-1482 | Chemical | denotes | methylprednisolone | MESH:D008775 |
656 | 1570-1588 | Chemical | denotes | methylprednisolone | MESH:D008775 |
652 | 1628-1636 | Species | denotes | patients | Tax:9606 |
661 | 1812-1819 | Species | denotes | patient | Tax:9606 |
662 | 1869-1878 | Species | denotes | 2019-nCoV | Tax:2697049 |
663 | 2013-2021 | Species | denotes | patients | Tax:9606 |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T1970 | 380-383 | Protein | denotes | B19 | https://www.uniprot.org/uniprot/P57058 |
T1971 | 656-659 | Protein | denotes | RBD | https://www.uniprot.org/uniprot/Q63492|https://www.uniprot.org/uniprot/Q63491|https://www.uniprot.org/uniprot/Q62815|https://www.uniprot.org/uniprot/Q62691|https://www.uniprot.org/uniprot/Q01542|https://www.uniprot.org/uniprot/P27732|https://www.uniprot.org/uniprot/O09024|https://www.uniprot.org/uniprot/O09023|https://www.uniprot.org/uniprot/O09022 |
T1980 | 871-874 | Protein | denotes | RBD | https://www.uniprot.org/uniprot/Q63492|https://www.uniprot.org/uniprot/Q63491|https://www.uniprot.org/uniprot/Q62815|https://www.uniprot.org/uniprot/Q62691|https://www.uniprot.org/uniprot/Q01542|https://www.uniprot.org/uniprot/P27732|https://www.uniprot.org/uniprot/O09024|https://www.uniprot.org/uniprot/O09023|https://www.uniprot.org/uniprot/O09022 |
LitCovid-sample-Enju
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T55819 | 0-3 | CD | denotes | 4.2 |
T56180 | 5-16 | JJ | denotes | Intravenous |
T2182 | 17-32 | NNS | denotes | immunoglobulins |
T41175 | 33-34 | -LRB- | denotes | ( |
T97867 | 34-38 | NN | denotes | IVIG |
T16816 | 38-39 | -RRB- | denotes | ) |
T56020 | 41-46 | CD | denotes | 4.2.1 |
T95212 | 48-58 | NN | denotes | Hypothesis |
T84611 | 58-59 | -COLON- | denotes | : |
T95417 | 60-64 | NN | denotes | IVIG |
T50853 | 65-73 | VBZ | denotes | contains |
T65863 | 74-75 | DT | denotes | a |
T68527 | 76-81 | JJ | denotes | large |
T83960 | 82-86 | NN | denotes | pool |
T57480 | 87-89 | IN | denotes | of |
T98962 | 90-95 | JJ | denotes | human |
T50450 | 96-106 | NNS | denotes | antibodies |
T12037 | 107-111 | NN | denotes | IVIG |
T52317 | 112-114 | VBZ | denotes | is |
T83276 | 115-117 | DT | denotes | an |
T47689 | 118-134 | JJ | denotes | immunomodulatory |
T32201 | 135-144 | NN | denotes | treatment |
T26744 | 145-154 | RB | denotes | currently |
T6595 | 155-161 | JJ | denotes | useful |
T61951 | 162-165 | IN | denotes | for |
T78252 | 166-167 | DT | denotes | a |
T96672 | 168-175 | NN | denotes | variety |
T75647 | 176-178 | IN | denotes | of |
T64366 | 179-184 | JJ | denotes | human |
T37666 | 185-193 | NNS | denotes | diseases |
T30663 | 194-198 | WDT | denotes | that |
T71611 | 199-204 | VBP | denotes | share |
T4369 | 205-207 | DT | denotes | an |
T95969 | 208-218 | JJ | denotes | idiopathic |
T35011 | 219-225 | NN | denotes | origin |
T94518 | 225-226 | -COMMA- | denotes | , |
T34533 | 227-234 | VBG | denotes | ranging |
T57537 | 235-239 | IN | denotes | from |
T47481 | 240-250 | JJ | denotes | autoimmune |
T10634 | 251-260 | NNS | denotes | disorders |
T96539 | 261-263 | TO | denotes | to |
T18270 | 264-271 | JJ | denotes | primary |
T92790 | 272-280 | NN | denotes | antibody |
T91348 | 281-293 | NNS | denotes | deficiencies |
T23275 | 295-299 | RB | denotes | Also |
T97483 | 299-300 | -COMMA- | denotes | , |
T12179 | 301-305 | NNP | denotes | IVIG |
T44219 | 306-309 | VBZ | denotes | has |
T10629 | 310-315 | VBN | denotes | shown |
T45168 | 316-325 | JJ | denotes | promising |
T67208 | 326-333 | NNS | denotes | results |
T77083 | 334-336 | IN | denotes | in |
T72909 | 337-341 | NN | denotes | case |
T84121 | 342-344 | IN | denotes | of |
T92712 | 345-351 | JJ | denotes | severe |
T79863 | 352-353 | -LRB- | denotes | ( |
T66824 | 353-357 | JJ | denotes | such |
T43956 | 358-360 | IN | denotes | as |
T9832 | 361-367 | NN | denotes | sepsis |
T13628 | 367-368 | -COMMA- | denotes | , |
T62406 | 369-379 | NN | denotes | Parvovirus |
T99835 | 380-383 | NN | denotes | B19 |
T14835 | 384-393 | NN | denotes | infection |
T15497 | 393-394 | -COMMA- | denotes | , |
T90831 | 395-399 | NNP | denotes | West |
T76795 | 400-404 | NNP | denotes | Nile |
T72325 | 405-410 | NN | denotes | virus |
T62294 | 411-423 | NN | denotes | encephalitis |
T79163 | 423-424 | -COMMA- | denotes | , |
T42313 | 425-428 | NN | denotes | HIV |
T73958 | 428-429 | -COMMA- | denotes | , |
T29310 | 430-441 | NNP | denotes | Clostridium |
T49447 | 442-451 | JJ | denotes | difficile |
T8038 | 452-462 | NNS | denotes | infections |
T10219 | 462-463 | -COMMA- | denotes | , |
T3443 | 464-477 | NN | denotes | Mycobacterium |
T55185 | 478-483 | NN | denotes | avium |
T2677 | 483-484 | -COMMA- | denotes | , |
T67405 | 485-498 | NN | denotes | Mycobacterium |
T65630 | 499-511 | NN | denotes | tuberculosis |
T60726 | 511-512 | -COMMA- | denotes | , |
T52785 | 513-516 | CC | denotes | and |
T44446 | 517-525 | NNP | denotes | Nocardia |
T90848 | 526-536 | NNS | denotes | infections |
T80386 | 536-537 | -RRB- | denotes | ) |
T6178 | 538-541 | CC | denotes | and |
T68317 | 542-551 | JJ | denotes | recurrent |
T17705 | 552-562 | NNS | denotes | infections |
T68999 | 563-565 | IN | denotes | in |
T18422 | 566-573 | JJ | denotes | primary |
T52471 | 574-584 | NNS | denotes | antibodies |
T62247 | 585-597 | NNS | denotes | deficiencies |
T55724 | 598-599 | -LRB- | denotes | [ |
T27007 | 599-601 | CD | denotes | 21 |
T97422 | 601-602 | -RRB- | denotes | ] |
T8813 | 604-608 | JJS | denotes | Most |
T48684 | 609-617 | NNS | denotes | patients |
T37814 | 618-625 | VBP | denotes | develop |
T41895 | 626-636 | NNS | denotes | antibodies |
T32237 | 637-644 | IN | denotes | against |
T55833 | 645-648 | DT | denotes | the |
T23466 | 649-651 | NN | denotes | NP |
T51386 | 652-655 | CC | denotes | and |
T97267 | 656-659 | NN | denotes | RBD |
T48238 | 660-662 | IN | denotes | of |
T17626 | 663-672 | NN | denotes | 2019-nCoV |
T87676 | 673-679 | IN | denotes | during |
T56543 | 680-683 | DT | denotes | the |
T74019 | 684-690 | JJ | denotes | second |
T36179 | 691-695 | NN | denotes | week |
T61939 | 696-701 | IN | denotes | after |
T53819 | 702-711 | NN | denotes | infection |
T47949 | 712-717 | NN | denotes | onset |
T10621 | 718-719 | -LRB- | denotes | [ |
T31327 | 719-721 | CD | denotes | 22 |
T53799 | 721-722 | -RRB- | denotes | ] |
T76985 | 724-732 | NN | denotes | Analysis |
T6758 | 733-735 | IN | denotes | of |
T88720 | 736-741 | NN | denotes | serum |
T73739 | 742-749 | NNS | denotes | samples |
T20072 | 750-759 | VBD | denotes | collected |
T30704 | 760-762 | CD | denotes | 14 |
T66398 | 763-765 | CC | denotes | or |
T43796 | 766-770 | JJR | denotes | more |
T64515 | 771-775 | NNS | denotes | days |
T88119 | 776-781 | IN | denotes | after |
T33297 | 782-789 | NN | denotes | symptom |
T78997 | 790-795 | NN | denotes | onset |
T69102 | 796-804 | VBD | denotes | revealed |
T51393 | 805-814 | NN | denotes | detection |
T49412 | 815-817 | IN | denotes | of |
T86080 | 818-821 | NN | denotes | IgG |
T42365 | 822-825 | CC | denotes | and |
T24248 | 826-829 | NN | denotes | IgM |
T84785 | 830-840 | NNS | denotes | antibodies |
T33598 | 841-848 | IN | denotes | against |
T65176 | 849-851 | NN | denotes | NP |
T29543 | 852-854 | IN | denotes | in |
T67075 | 855-857 | CD | denotes | 94 |
T4274 | 857-858 | NN | denotes | % |
T73088 | 859-862 | CC | denotes | and |
T74097 | 863-865 | CD | denotes | 88 |
T71868 | 865-866 | NN | denotes | % |
T54079 | 867-870 | CC | denotes | and |
T73098 | 871-874 | NN | denotes | RBD |
T69539 | 875-877 | IN | denotes | in |
T87988 | 878-881 | CD | denotes | 100 |
T78691 | 881-882 | NN | denotes | % |
T18580 | 883-886 | CC | denotes | and |
T46489 | 887-889 | CD | denotes | 94 |
T64615 | 889-890 | NN | denotes | % |
T60810 | 891-896 | IN | denotes | among |
T38563 | 897-905 | NNS | denotes | patients |
T93829 | 906-910 | IN | denotes | with |
T24980 | 911-918 | NN | denotes | COVID19 |
T89545 | 920-927 | NNS | denotes | Studies |
T44838 | 928-940 | RB | denotes | consistently |
T54246 | 941-945 | VBP | denotes | show |
T20581 | 946-950 | IN | denotes | that |
T54967 | 951-960 | VBN | denotes | increased |
T27422 | 961-975 | NN | denotes | immunoglobulin |
T48431 | 976-982 | NNS | denotes | levels |
T7060 | 983-992 | VBP | denotes | accompany |
T92743 | 993-996 | DT | denotes | the |
T24866 | 997-1007 | NN | denotes | transition |
T9522 | 1008-1012 | IN | denotes | from |
T69120 | 1013-1018 | JJ | denotes | early |
T81312 | 1019-1021 | TO | denotes | to |
T7048 | 1022-1026 | JJ | denotes | late |
T25388 | 1027-1033 | NN | denotes | course |
T44741 | 1034-1036 | IN | denotes | of |
T20679 | 1037-1044 | NN | denotes | COVID19 |
T6735 | 1046-1048 | PRP | denotes | It |
T32751 | 1049-1054 | VBZ | denotes | poses |
T41840 | 1055-1058 | DT | denotes | the |
T21434 | 1059-1070 | NN | denotes | possibility |
T75450 | 1071-1075 | IN | denotes | that |
T55251 | 1076-1080 | NN | denotes | IVIG |
T48129 | 1081-1088 | NN | denotes | therapy |
T90120 | 1089-1094 | MD | denotes | might |
T91321 | 1095-1099 | VB | denotes | help |
T89890 | 1100-1102 | TO | denotes | to |
T64443 | 1103-1113 | VB | denotes | accelerate |
T5150 | 1114-1122 | NN | denotes | recovery |
T43666 | 1123-1127 | IN | denotes | from |
T85289 | 1128-1136 | NN | denotes | COVID-19 |
T72940 | 1139-1144 | CD | denotes | 4.2.2 |
T31699 | 1146-1155 | NNP | denotes | Rationale |
T6254 | 1155-1156 | -COLON- | denotes | : |
T80516 | 1157-1161 | NN | denotes | IVIG |
T69063 | 1162-1167 | MD | denotes | might |
T22631 | 1168-1172 | VB | denotes | help |
T88012 | 1173-1175 | TO | denotes | to |
T98862 | 1176-1183 | VB | denotes | improve |
T98671 | 1184-1187 | DT | denotes | the |
T20348 | 1188-1195 | NN | denotes | outcome |
T65200 | 1196-1198 | IN | denotes | of |
T90061 | 1199-1207 | NNS | denotes | patients |
T66297 | 1208-1212 | IN | denotes | with |
T53417 | 1213-1221 | NN | denotes | COVID-19 |
T18993 | 1222-1225 | DT | denotes | The |
T21718 | 1226-1231 | NN | denotes | study |
T64168 | 1232-1233 | -LRB- | denotes | [ |
T66430 | 1233-1235 | CD | denotes | 23 |
T95152 | 1235-1236 | -RRB- | denotes | ] |
T31198 | 1237-1245 | VBD | denotes | included |
T55004 | 1246-1249 | CD | denotes | ten |
T65830 | 1250-1258 | NNS | denotes | patients |
T56952 | 1259-1263 | IN | denotes | with |
T98815 | 1264-1272 | NN | denotes | COVID-19 |
T69048 | 1273-1276 | WP | denotes | who |
T75376 | 1277-1289 | VBD | denotes | demonstrated |
T59786 | 1290-1299 | VBG | denotes | worsening |
T24326 | 1300-1308 | NNS | denotes | symptoms |
T13700 | 1308-1309 | -COMMA- | denotes | , |
T79561 | 1310-1314 | FW | denotes | e.g. |
T83448 | 1314-1315 | -COMMA- | denotes | , |
T77014 | 1316-1325 | VBD | denotes | decreased |
T40148 | 1326-1336 | NN | denotes | lymphocyte |
T31095 | 1337-1342 | NN | denotes | count |
T13833 | 1343-1346 | CC | denotes | and |
T80531 | 1347-1356 | VBD | denotes | decreased |
T26060 | 1357-1366 | NN | denotes | PaO2/FIO2 |
T3471 | 1367-1372 | NN | denotes | ratio |
T11859 | 1373-1376 | CC | denotes | and |
T6067 | 1377-1383 | NN | denotes | oxygen |
T65980 | 1384-1394 | NN | denotes | saturation |
T58632 | 1394-1395 | -COMMA- | denotes | , |
T52543 | 1396-1405 | VBG | denotes | following |
T84435 | 1406-1415 | NN | denotes | treatment |
T44273 | 1416-1420 | IN | denotes | with |
T99668 | 1421-1422 | DT | denotes | a |
T65524 | 1423-1433 | JJ | denotes | short-term |
T66169 | 1434-1447 | JJ | denotes | moderate-dose |
T25963 | 1448-1462 | NN | denotes | corticosteroid |
T54040 | 1463-1464 | -LRB- | denotes | ( |
T15835 | 1464-1482 | NN | denotes | methylprednisolone |
T75851 | 1483-1490 | NN | denotes | 80 mg/d |
T55858 | 1490-1491 | -RRB- | denotes | ) |
T6426 | 1492-1496 | CC | denotes | plus |
T60445 | 1497-1511 | NN | denotes | immunoglobulin |
T91733 | 1512-1513 | -LRB- | denotes | ( |
T10263 | 1513-1519 | CD | denotes | 10 g/d |
T89099 | 1519-1520 | -RRB- | denotes | ) |
T32422 | 1522-1527 | IN | denotes | After |
T38661 | 1528-1537 | VBG | denotes | switching |
T47400 | 1538-1540 | TO | denotes | to |
T27854 | 1541-1544 | DT | denotes | the |
T88178 | 1545-1551 | JJ | denotes | double |
T22917 | 1552-1556 | NN | denotes | dose |
T27562 | 1557-1559 | IN | denotes | of |
T69861 | 1560-1569 | NN | denotes | 1600 mg/d |
T26688 | 1570-1588 | NN | denotes | methylprednisolone |
T91618 | 1589-1593 | CC | denotes | plus |
T63033 | 1594-1600 | NN | denotes | 20 g/d |
T82872 | 1601-1615 | NN | denotes | immunoglobulin |
T48110 | 1615-1616 | -COMMA- | denotes | , |
T64285 | 1617-1620 | DT | denotes | all |
T67888 | 1621-1623 | IN | denotes | of |
T16788 | 1624-1627 | DT | denotes | the |
T67776 | 1628-1636 | NNS | denotes | patients |
T6163 | 1637-1645 | VBN | denotes | improved |
T27596 | 1646-1648 | IN | denotes | in |
T10929 | 1649-1652 | DT | denotes | the |
T87507 | 1653-1661 | JJ | denotes | clinical |
T10805 | 1661-1662 | -COMMA- | denotes | , |
T49266 | 1663-1673 | NN | denotes | laboratory |
T95692 | 1673-1674 | -COMMA- | denotes | , |
T51590 | 1675-1678 | CC | denotes | and |
T63732 | 1679-1691 | JJ | denotes | paraclinical |
T58895 | 1692-1700 | NNS | denotes | outcomes |
T85504 | 1702-1709 | JJ | denotes | Passive |
T86520 | 1710-1722 | NN | denotes | immunization |
T22143 | 1723-1731 | VBZ | denotes | protects |
T80547 | 1732-1739 | IN | denotes | against |
T21735 | 1740-1747 | NN | denotes | disease |
T15590 | 1747-1748 | -COMMA- | denotes | , |
T4169 | 1749-1752 | CC | denotes | and |
T50400 | 1753-1755 | IN | denotes | so |
T4187 | 1756-1758 | PRP | denotes | it |
T38504 | 1759-1765 | MD | denotes | should |
T8453 | 1766-1768 | VB | denotes | be |
T27914 | 1769-1781 | VBN | denotes | administered |
T25991 | 1782-1784 | RB | denotes | as |
T54707 | 1785-1790 | RB | denotes | early |
T29802 | 1791-1793 | IN | denotes | as |
T24869 | 1794-1802 | JJ | denotes | possible |
T10896 | 1803-1807 | WRB | denotes | when |
T25638 | 1808-1811 | DT | denotes | the |
T29960 | 1812-1819 | NN | denotes | patient |
T20464 | 1820-1822 | VBZ | denotes | is |
T3036 | 1823-1832 | VBN | denotes | diagnosed |
T87261 | 1834-1841 | NNS | denotes | Studies |
T96660 | 1842-1846 | VBP | denotes | show |
T29990 | 1847-1851 | IN | denotes | that |
T81080 | 1852-1855 | DT | denotes | the |
T36950 | 1856-1861 | JJ | denotes | viral |
T53426 | 1862-1865 | NN | denotes | RNA |
T78293 | 1866-1868 | IN | denotes | of |
T18048 | 1869-1878 | NN | denotes | 2019-nCoV |
T93176 | 1879-1886 | VBZ | denotes | reaches |
T83675 | 1887-1890 | PRP-DOLLAR- | denotes | its |
T2594 | 1891-1895 | NN | denotes | peak |
T62926 | 1896-1902 | IN | denotes | during |
T35185 | 1903-1906 | DT | denotes | the |
T47524 | 1907-1912 | JJ | denotes | first |
T79772 | 1913-1917 | NN | denotes | week |
T85972 | 1918-1921 | CC | denotes | and |
T60597 | 1922-1926 | RB | denotes | then |
T18711 | 1927-1936 | RB | denotes | gradually |
T40522 | 1937-1946 | VBZ | denotes | decreases |
T67874 | 1947-1950 | CC | denotes | and |
T80013 | 1951-1955 | IN | denotes | that |
T48373 | 1956-1959 | NN | denotes | IgG |
T85015 | 1960-1963 | CC | denotes | and |
T48892 | 1964-1967 | NN | denotes | IgM |
T97802 | 1968-1973 | VBP | denotes | begin |
T54813 | 1974-1976 | TO | denotes | to |
T87582 | 1977-1981 | VB | denotes | rise |
T15243 | 1982-1986 | IN | denotes | from |
T79089 | 1987-1990 | DT | denotes | the |
T92830 | 1991-1995 | JJ | denotes | 10th |
T91091 | 1996-1999 | NN | denotes | day |
T75308 | 2000-2002 | IN | denotes | so |
T98992 | 2003-2007 | IN | denotes | that |
T91226 | 2008-2012 | JJS | denotes | most |
T66875 | 2013-2021 | NNS | denotes | patients |
T44373 | 2022-2026 | VBP | denotes | have |
T45012 | 2027-2037 | JJ | denotes | anti-viral |
T2304 | 2038-2048 | NNS | denotes | antibodies |
T90719 | 2049-2051 | IN | denotes | by |
T66178 | 2052-2055 | DT | denotes | the |
T38757 | 2056-2060 | JJ | denotes | 14th |
T73930 | 2061-2064 | NN | denotes | day |
R83120 | T2182 | T55819 | arg1Of | immunoglobulins,4.2 |
R86188 | T2182 | T56180 | arg1Of | immunoglobulins,Intravenous |
R54403 | T2182 | T41175 | arg1Of | immunoglobulins,( |
R42896 | T97867 | T41175 | arg2Of | IVIG,( |
R53615 | T16816 | T41175 | arg3Of | ),( |
R37061 | T95212 | T56020 | arg1Of | Hypothesis,4.2.1 |
R21455 | T95212 | T84611 | arg1Of | Hypothesis,: |
R41659 | T50853 | T84611 | arg2Of | contains,: |
R26320 | T95417 | T50853 | arg1Of | IVIG,contains |
R55634 | T83960 | T50853 | arg2Of | pool,contains |
R11871 | T83960 | T65863 | arg1Of | pool,a |
R81126 | T83960 | T68527 | arg1Of | pool,large |
R87985 | T83960 | T57480 | arg1Of | pool,of |
R85206 | T50450 | T57480 | arg2Of | antibodies,of |
R95689 | T50450 | T98962 | arg1Of | antibodies,human |
R7397 | T12037 | T52317 | arg1Of | IVIG,is |
R59827 | T32201 | T52317 | arg2Of | treatment,is |
R45922 | T32201 | T83276 | arg1Of | treatment,an |
R32666 | T32201 | T47689 | arg1Of | treatment,immunomodulatory |
R38821 | T32201 | T26744 | arg1Of | treatment,currently |
R80185 | T26744 | T6595 | arg1Of | currently,useful |
R62385 | T6595 | T61951 | arg1Of | useful,for |
R78431 | T96672 | T61951 | arg2Of | variety,for |
R3964 | T96672 | T78252 | arg1Of | variety,a |
R72167 | T96672 | T75647 | arg1Of | variety,of |
R82814 | T37666 | T75647 | arg2Of | diseases,of |
R55274 | T37666 | T64366 | arg1Of | diseases,human |
R31515 | T37666 | T30663 | arg1Of | diseases,that |
R12726 | T37666 | T71611 | arg1Of | diseases,share |
R20851 | T35011 | T71611 | arg2Of | origin,share |
R86274 | T35011 | T4369 | arg1Of | origin,an |
R95215 | T35011 | T95969 | arg1Of | origin,idiopathic |
R10701 | T32201 | T94518 | arg1Of | treatment,"," |
R19665 | T32201 | T34533 | arg1Of | treatment,ranging |
R89530 | T34533 | T57537 | arg1Of | ranging,from |
R77337 | T10634 | T57537 | arg2Of | disorders,from |
R63281 | T10634 | T47481 | arg1Of | disorders,autoimmune |
R45693 | T34533 | T96539 | arg1Of | ranging,to |
R65268 | T91348 | T96539 | arg2Of | deficiencies,to |
R94792 | T91348 | T18270 | arg1Of | deficiencies,primary |
R91107 | T91348 | T92790 | arg1Of | deficiencies,antibody |
R9941 | T10629 | T23275 | arg1Of | shown,Also |
R28227 | T10629 | T97483 | arg1Of | shown,"," |
R92669 | T12179 | T44219 | arg1Of | IVIG,has |
R31307 | T10629 | T44219 | arg2Of | shown,has |
R77637 | T12179 | T10629 | arg1Of | IVIG,shown |
R23512 | T67208 | T10629 | arg2Of | results,shown |
R8504 | T67208 | T45168 | arg1Of | results,promising |
R20697 | T67208 | T77083 | arg1Of | results,in |
R78894 | T72909 | T77083 | arg2Of | case,in |
R82064 | T72909 | T84121 | arg1Of | case,of |
R98709 | T6178 | T84121 | arg2Of | and,of |
R28624 | T52785 | T92712 | arg1Of | and,severe |
R80380 | T52785 | T79863 | arg2Of | and,( |
R24626 | T80386 | T79863 | arg3Of | ),( |
R19944 | T43956 | T66824 | arg1Of | as,such |
R49580 | T52785 | T43956 | arg1Of | and,as |
R37840 | T13628 | T43956 | arg2Of | ",",as |
R28995 | T9832 | T13628 | arg1Of | sepsis,"," |
R16863 | T14835 | T13628 | arg2Of | infection,"," |
R40263 | T14835 | T62406 | arg1Of | infection,Parvovirus |
R95673 | T14835 | T99835 | arg1Of | infection,B19 |
R52070 | T13628 | T15497 | arg1Of | ",","," |
R13275 | T62294 | T15497 | arg2Of | encephalitis,"," |
R22619 | T76795 | T90831 | arg1Of | Nile,West |
R23224 | T62294 | T76795 | arg1Of | encephalitis,Nile |
R99263 | T62294 | T72325 | arg1Of | encephalitis,virus |
R15788 | T62294 | T79163 | arg1Of | encephalitis,"," |
R54321 | T42313 | T79163 | arg2Of | HIV,"," |
R99309 | T52785 | T73958 | arg1Of | and,"," |
R85642 | T8038 | T29310 | arg1Of | infections,Clostridium |
R55554 | T8038 | T49447 | arg1Of | infections,difficile |
R94197 | T8038 | T10219 | arg1Of | infections,"," |
R30216 | T55185 | T10219 | arg2Of | avium,"," |
R46944 | T55185 | T3443 | arg1Of | avium,Mycobacterium |
R36023 | T10219 | T2677 | arg1Of | ",","," |
R30475 | T65630 | T2677 | arg2Of | tuberculosis,"," |
R32473 | T65630 | T67405 | arg1Of | tuberculosis,Mycobacterium |
R79700 | T52785 | T60726 | arg1Of | and,"," |
R5424 | T2677 | T52785 | arg1Of | ",",and |
R82963 | T90848 | T52785 | arg2Of | infections,and |
R12367 | T90848 | T44446 | arg1Of | infections,Nocardia |
R36176 | T52785 | T6178 | arg1Of | and,and |
R5432 | T17705 | T6178 | arg2Of | infections,and |
R7624 | T17705 | T68317 | arg1Of | infections,recurrent |
R48790 | T6178 | T68999 | arg1Of | and,in |
R33893 | T62247 | T68999 | arg2Of | deficiencies,in |
R41252 | T62247 | T18422 | arg1Of | deficiencies,primary |
R34450 | T62247 | T52471 | arg1Of | deficiencies,antibodies |
R24969 | T62247 | T55724 | arg1Of | deficiencies,[ |
R29860 | T27007 | T55724 | arg2Of | 21,[ |
R45347 | T97422 | T55724 | arg3Of | ],[ |
R18045 | T48684 | T8813 | arg1Of | patients,Most |
R91845 | T48684 | T37814 | arg1Of | patients,develop |
R13100 | T41895 | T37814 | arg2Of | antibodies,develop |
R35710 | T37814 | T32237 | arg1Of | develop,against |
R20807 | T51386 | T32237 | arg2Of | and,against |
R6800 | T51386 | T55833 | arg1Of | and,the |
R22109 | T23466 | T51386 | arg1Of | NP,and |
R81797 | T97267 | T51386 | arg2Of | RBD,and |
R91140 | T51386 | T48238 | arg1Of | and,of |
R87740 | T17626 | T48238 | arg2Of | 2019-nCoV,of |
R8876 | T37814 | T87676 | arg1Of | develop,during |
R35461 | T36179 | T87676 | arg2Of | week,during |
R97441 | T36179 | T56543 | arg1Of | week,the |
R2585 | T36179 | T74019 | arg1Of | week,second |
R34363 | T37814 | T61939 | arg1Of | develop,after |
R46687 | T47949 | T61939 | arg2Of | onset,after |
R33556 | T47949 | T53819 | arg1Of | onset,infection |
R6993 | T37814 | T10621 | arg1Of | develop,[ |
R3294 | T31327 | T10621 | arg2Of | 22,[ |
R78306 | T53799 | T10621 | arg3Of | ],[ |
R98284 | T76985 | T6758 | arg1Of | Analysis,of |
R72949 | T73739 | T6758 | arg2Of | samples,of |
R94093 | T73739 | T88720 | arg1Of | samples,serum |
R64474 | T76985 | T20072 | arg1Of | Analysis,collected |
R79737 | T64515 | T20072 | arg2Of | days,collected |
R31087 | T64515 | T30704 | arg1Of | days,14 |
R58487 | T30704 | T66398 | arg1Of | 14,or |
R48701 | T30704 | T43796 | arg1Of | 14,more |
R91116 | T20072 | T88119 | arg1Of | collected,after |
R29180 | T69102 | T88119 | arg2Of | revealed,after |
R61094 | T78997 | T33297 | arg1Of | onset,symptom |
R30751 | T78997 | T69102 | arg1Of | onset,revealed |
R85646 | T51393 | T69102 | arg2Of | detection,revealed |
R94930 | T51393 | T49412 | arg1Of | detection,of |
R15007 | T84785 | T49412 | arg2Of | antibodies,of |
R35220 | T84785 | T86080 | arg1Of | antibodies,IgG |
R17029 | T86080 | T42365 | arg1Of | IgG,and |
R36223 | T24248 | T42365 | arg2Of | IgM,and |
R4871 | T84785 | T24248 | arg1Of | antibodies,IgM |
R37373 | T51393 | T33598 | arg1Of | detection,against |
R80609 | T65176 | T33598 | arg2Of | NP,against |
R29116 | T51393 | T29543 | arg1Of | detection,in |
R74727 | T54079 | T29543 | arg2Of | and,in |
R31620 | T4274 | T67075 | arg1Of | %,94 |
R41074 | T71868 | T4274 | arg1Of | %,% |
R32415 | T4274 | T73088 | arg1Of | %,and |
R53047 | T74097 | T73088 | arg2Of | 88,and |
R60224 | T71868 | T74097 | arg1Of | %,88 |
R30825 | T71868 | T54079 | arg1Of | %,and |
R92508 | T73098 | T54079 | arg2Of | RBD,and |
R99739 | T54079 | T69539 | arg1Of | and,in |
R9744 | T64615 | T69539 | arg2Of | %,in |
R73124 | T78691 | T87988 | arg1Of | %,100 |
R67370 | T64615 | T78691 | arg1Of | %,% |
R15728 | T78691 | T18580 | arg1Of | %,and |
R74845 | T46489 | T18580 | arg2Of | 94,and |
R42305 | T64615 | T46489 | arg1Of | %,94 |
R38001 | T51393 | T60810 | arg1Of | detection,among |
R89986 | T38563 | T60810 | arg2Of | patients,among |
R54593 | T38563 | T93829 | arg1Of | patients,with |
R6445 | T24980 | T93829 | arg2Of | COVID19,with |
R86911 | T54246 | T44838 | arg1Of | show,consistently |
R41127 | T89545 | T54246 | arg1Of | Studies,show |
R52555 | T7060 | T54246 | arg2Of | accompany,show |
R1890 | T7060 | T20581 | arg1Of | accompany,that |
R15150 | T48431 | T54967 | arg2Of | levels,increased |
R79272 | T48431 | T27422 | arg1Of | levels,immunoglobulin |
R9994 | T48431 | T7060 | arg1Of | levels,accompany |
R27595 | T24866 | T7060 | arg2Of | transition,accompany |
R10059 | T24866 | T92743 | arg1Of | transition,the |
R64970 | T24866 | T9522 | arg1Of | transition,from |
R11593 | T25388 | T9522 | arg2Of | course,from |
R11280 | T7048 | T69120 | arg1Of | late,early |
R61089 | T7048 | T81312 | arg1Of | late,to |
R36970 | T25388 | T7048 | arg1Of | course,late |
R76248 | T25388 | T44741 | arg1Of | course,of |
R16578 | T20679 | T44741 | arg2Of | COVID19,of |
R93295 | T6735 | T32751 | arg1Of | It,poses |
R68469 | T21434 | T32751 | arg2Of | possibility,poses |
R17888 | T21434 | T41840 | arg1Of | possibility,the |
R71902 | T91321 | T21434 | arg2Of | help,possibility |
R4510 | T91321 | T75450 | arg1Of | help,that |
R34056 | T48129 | T55251 | arg1Of | therapy,IVIG |
R30440 | T48129 | T90120 | arg1Of | therapy,might |
R46659 | T91321 | T90120 | arg2Of | help,might |
R94505 | T48129 | T91321 | arg1Of | therapy,help |
R59227 | T64443 | T91321 | arg2Of | accelerate,help |
R39248 | T64443 | T89890 | arg1Of | accelerate,to |
R27615 | T48129 | T64443 | arg1Of | therapy,accelerate |
R41612 | T5150 | T64443 | arg2Of | recovery,accelerate |
R13579 | T5150 | T43666 | arg1Of | recovery,from |
R80924 | T85289 | T43666 | arg2Of | COVID-19,from |
R82140 | T31699 | T72940 | arg1Of | Rationale,4.2.2 |
R99597 | T31699 | T6254 | arg1Of | Rationale,: |
R25082 | T22631 | T6254 | arg2Of | help,: |
R45006 | T80516 | T69063 | arg1Of | IVIG,might |
R51148 | T22631 | T69063 | arg2Of | help,might |
R70932 | T80516 | T22631 | arg1Of | IVIG,help |
R90242 | T98862 | T22631 | arg2Of | improve,help |
R33852 | T98862 | T88012 | arg1Of | improve,to |
R33240 | T80516 | T98862 | arg1Of | IVIG,improve |
R77199 | T20348 | T98862 | arg2Of | outcome,improve |
R11936 | T20348 | T98671 | arg1Of | outcome,the |
R19763 | T20348 | T65200 | arg1Of | outcome,of |
R2046 | T90061 | T65200 | arg2Of | patients,of |
R70326 | T90061 | T66297 | arg1Of | patients,with |
R67204 | T53417 | T66297 | arg2Of | COVID-19,with |
R50369 | T21718 | T18993 | arg1Of | study,The |
R14407 | T21718 | T64168 | arg1Of | study,[ |
R76274 | T66430 | T64168 | arg2Of | 23,[ |
R38202 | T95152 | T64168 | arg3Of | ],[ |
R86526 | T21718 | T31198 | arg1Of | study,included |
R31769 | T65830 | T31198 | arg2Of | patients,included |
R46612 | T65830 | T55004 | arg1Of | patients,ten |
R25333 | T65830 | T56952 | arg1Of | patients,with |
R9661 | T98815 | T56952 | arg2Of | COVID-19,with |
R66734 | T98815 | T69048 | arg1Of | COVID-19,who |
R31347 | T98815 | T75376 | arg1Of | COVID-19,demonstrated |
R59919 | T24326 | T75376 | arg2Of | symptoms,demonstrated |
R40351 | T24326 | T59786 | arg1Of | symptoms,worsening |
R92905 | T31198 | T13700 | arg1Of | included,"," |
R16771 | T13833 | T13700 | arg2Of | and,"," |
R26629 | T13833 | T79561 | arg1Of | and,e.g. |
R4076 | T13833 | T83448 | arg1Of | and,"," |
R17219 | T21718 | T77014 | arg1Of | study,decreased |
R22057 | T31095 | T77014 | arg2Of | count,decreased |
R79029 | T31095 | T40148 | arg1Of | count,lymphocyte |
R1770 | T77014 | T13833 | arg1Of | decreased,and |
R37459 | T80531 | T13833 | arg2Of | decreased,and |
R47262 | T21718 | T80531 | arg1Of | study,decreased |
R34129 | T11859 | T80531 | arg2Of | and,decreased |
R19341 | T3471 | T26060 | arg1Of | ratio,PaO2/FIO2 |
R92577 | T3471 | T11859 | arg1Of | ratio,and |
R40508 | T65980 | T11859 | arg2Of | saturation,and |
R18986 | T65980 | T6067 | arg1Of | saturation,oxygen |
R39324 | T13833 | T58632 | arg1Of | and,"," |
R49635 | T13833 | T52543 | arg1Of | and,following |
R4003 | T6426 | T52543 | arg2Of | plus,following |
R22662 | T84435 | T44273 | arg1Of | treatment,with |
R78212 | T25963 | T44273 | arg2Of | corticosteroid,with |
R70976 | T25963 | T99668 | arg1Of | corticosteroid,a |
R50003 | T25963 | T65524 | arg1Of | corticosteroid,short-term |
R2970 | T25963 | T66169 | arg1Of | corticosteroid,moderate-dose |
R89182 | T25963 | T54040 | arg1Of | corticosteroid,( |
R82941 | T75851 | T54040 | arg2Of | 80 mg/d,( |
R99800 | T55858 | T54040 | arg3Of | ),( |
R95496 | T75851 | T15835 | arg1Of | 80 mg/d,methylprednisolone |
R36752 | T84435 | T6426 | arg1Of | treatment,plus |
R79540 | T60445 | T6426 | arg2Of | immunoglobulin,plus |
R41260 | T60445 | T91733 | arg1Of | immunoglobulin,( |
R75502 | T10263 | T91733 | arg2Of | 10 g/d,( |
R50386 | T89099 | T91733 | arg3Of | ),( |
R26413 | T6163 | T32422 | arg1Of | improved,After |
R62745 | T38661 | T32422 | arg2Of | switching,After |
R35046 | T64285 | T38661 | arg1Of | all,switching |
R97543 | T38661 | T47400 | arg1Of | switching,to |
R45642 | T22917 | T47400 | arg2Of | dose,to |
R79576 | T22917 | T27854 | arg1Of | dose,the |
R56085 | T22917 | T88178 | arg1Of | dose,double |
R64025 | T22917 | T27562 | arg1Of | dose,of |
R36622 | T91618 | T27562 | arg2Of | plus,of |
R47040 | T26688 | T69861 | arg1Of | methylprednisolone,1600 mg/d |
R96957 | T26688 | T91618 | arg1Of | methylprednisolone,plus |
R59825 | T82872 | T91618 | arg2Of | immunoglobulin,plus |
R2563 | T82872 | T63033 | arg1Of | immunoglobulin,20 g/d |
R17542 | T6163 | T48110 | arg1Of | improved,"," |
R33163 | T64285 | T67888 | arg1Of | all,of |
R47106 | T67776 | T67888 | arg2Of | patients,of |
R68832 | T67776 | T16788 | arg1Of | patients,the |
R41521 | T64285 | T6163 | arg1Of | all,improved |
R92060 | T6163 | T27596 | arg1Of | improved,in |
R79224 | T58895 | T27596 | arg2Of | outcomes,in |
R14909 | T58895 | T10929 | arg1Of | outcomes,the |
R43963 | T58895 | T87507 | arg1Of | outcomes,clinical |
R46705 | T87507 | T10805 | arg1Of | clinical,"," |
R31644 | T49266 | T10805 | arg2Of | laboratory,"," |
R53992 | T58895 | T49266 | arg1Of | outcomes,laboratory |
R52803 | T51590 | T95692 | arg1Of | and,"," |
R16749 | T10805 | T51590 | arg1Of | ",",and |
R63324 | T63732 | T51590 | arg2Of | paraclinical,and |
R41915 | T58895 | T63732 | arg1Of | outcomes,paraclinical |
R55232 | T86520 | T85504 | arg1Of | immunization,Passive |
R10991 | T86520 | T22143 | arg1Of | immunization,protects |
R69581 | T22143 | T80547 | arg1Of | protects,against |
R58848 | T21735 | T80547 | arg2Of | disease,against |
R89140 | T4169 | T15590 | arg1Of | and,"," |
R87834 | T22143 | T4169 | arg1Of | protects,and |
R91588 | T27914 | T4169 | arg2Of | administered,and |
R50799 | T27914 | T50400 | arg1Of | administered,so |
R82498 | T4187 | T38504 | arg1Of | it,should |
R94705 | T27914 | T38504 | arg2Of | administered,should |
R14592 | T4187 | T8453 | arg1Of | it,be |
R28181 | T27914 | T8453 | arg2Of | administered,be |
R94232 | T4187 | T27914 | arg2Of | it,administered |
R68805 | T54707 | T25991 | arg1Of | early,as |
R98402 | T27914 | T54707 | arg1Of | administered,early |
R46464 | T54707 | T29802 | arg1Of | early,as |
R22163 | T24869 | T29802 | arg2Of | possible,as |
R45063 | T27914 | T10896 | arg1Of | administered,when |
R89732 | T3036 | T10896 | arg2Of | diagnosed,when |
R29783 | T29960 | T25638 | arg1Of | patient,the |
R50945 | T29960 | T20464 | arg1Of | patient,is |
R9347 | T3036 | T20464 | arg2Of | diagnosed,is |
R96008 | T29960 | T3036 | arg2Of | patient,diagnosed |
R15494 | T87261 | T96660 | arg1Of | Studies,show |
R35568 | T67874 | T96660 | arg2Of | and,show |
R23868 | T85972 | T29990 | arg1Of | and,that |
R73123 | T53426 | T81080 | arg1Of | RNA,the |
R53013 | T53426 | T36950 | arg1Of | RNA,viral |
R7573 | T53426 | T78293 | arg1Of | RNA,of |
R81045 | T18048 | T78293 | arg2Of | 2019-nCoV,of |
R2548 | T53426 | T93176 | arg1Of | RNA,reaches |
R70781 | T2594 | T93176 | arg2Of | peak,reaches |
R53482 | T2594 | T83675 | arg1Of | peak,its |
R57386 | T93176 | T62926 | arg1Of | reaches,during |
R56679 | T79772 | T62926 | arg2Of | week,during |
R40741 | T79772 | T35185 | arg1Of | week,the |
R25803 | T79772 | T47524 | arg1Of | week,first |
R42816 | T93176 | T85972 | arg1Of | reaches,and |
R99315 | T40522 | T85972 | arg2Of | decreases,and |
R84704 | T40522 | T60597 | arg1Of | decreases,then |
R48610 | T40522 | T18711 | arg1Of | decreases,gradually |
R43001 | T53426 | T40522 | arg1Of | RNA,decreases |
R36109 | T85972 | T67874 | arg1Of | and,and |
R96845 | T80013 | T67874 | arg2Of | that,and |
R2631 | T97802 | T80013 | arg2Of | begin,that |
R52755 | T48373 | T85015 | arg1Of | IgG,and |
R60239 | T48892 | T85015 | arg2Of | IgM,and |
R48496 | T85015 | T97802 | arg1Of | and,begin |
R27628 | T87582 | T97802 | arg2Of | rise,begin |
R58171 | T87582 | T54813 | arg1Of | rise,to |
R42427 | T85015 | T87582 | arg1Of | and,rise |
R47112 | T87582 | T15243 | arg1Of | rise,from |
R54860 | T91091 | T15243 | arg2Of | day,from |
R40258 | T91091 | T79089 | arg1Of | day,the |
R81041 | T91091 | T92830 | arg1Of | day,10th |
R10340 | T87582 | T75308 | arg1Of | rise,so |
R28808 | T44373 | T75308 | arg2Of | have,so |
R89374 | T75308 | T98992 | arg1Of | so,that |
R10355 | T66875 | T91226 | arg1Of | patients,most |
R53372 | T66875 | T44373 | arg1Of | patients,have |
R13811 | T2304 | T44373 | arg2Of | antibodies,have |
R80044 | T2304 | T45012 | arg1Of | antibodies,anti-viral |
R71283 | T44373 | T90719 | arg1Of | have,by |
R16551 | T73930 | T90719 | arg2Of | day,by |
R27976 | T73930 | T66178 | arg1Of | day,the |
R35060 | T73930 | T38757 | arg1Of | day,14th |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T134 | 17-32 | Body_part | denotes | immunoglobulins | http://purl.org/sig/ont/fma/fma62871 |
T135 | 272-280 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T136 | 425-428 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T137 | 736-741 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
T138 | 818-821 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T139 | 826-829 | Body_part | denotes | IgM | http://purl.org/sig/ont/fma/fma62873 |
T140 | 961-975 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
T141 | 1326-1336 | Body_part | denotes | lymphocyte | http://purl.org/sig/ont/fma/fma62863 |
T142 | 1497-1511 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
T143 | 1601-1615 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
T144 | 1862-1865 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T145 | 1956-1959 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T146 | 1964-1967 | Body_part | denotes | IgM | http://purl.org/sig/ont/fma/fma62873 |
LitCovid-sample-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T119 | 240-260 | Disease | denotes | autoimmune disorders | http://purl.obolibrary.org/obo/MONDO_0007179 |
T120 | 264-293 | Disease | denotes | primary antibody deficiencies | http://purl.obolibrary.org/obo/MONDO_0015517 |
T121 | 384-393 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T122 | 405-423 | Disease | denotes | virus encephalitis | http://purl.obolibrary.org/obo/MONDO_0006009 |
T123 | 430-462 | Disease | denotes | Clostridium difficile infections | http://purl.obolibrary.org/obo/MONDO_0000705 |
T124 | 499-511 | Disease | denotes | tuberculosis | http://purl.obolibrary.org/obo/MONDO_0018076 |
T125 | 517-536 | Disease | denotes | Nocardia infections | http://purl.obolibrary.org/obo/MONDO_0017776 |
T126 | 552-565 | Disease | denotes | infections in | http://purl.obolibrary.org/obo/MONDO_0005550 |
T127 | 566-597 | Disease | denotes | primary antibodies deficiencies | http://purl.obolibrary.org/obo/MONDO_0015517 |
T128 | 702-711 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T129 | 911-918 | Disease | denotes | COVID19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T130 | 1037-1044 | Disease | denotes | COVID19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T131 | 1128-1136 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T132 | 1213-1221 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T133 | 1264-1272 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-sample-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T4 | 240-260 | Phenotype | denotes | autoimmune disorders | http://purl.obolibrary.org/obo/HP_0002960 |
T5 | 361-367 | Phenotype | denotes | sepsis | http://purl.obolibrary.org/obo/HP_0100806 |
T6 | 411-423 | Phenotype | denotes | encephalitis | http://purl.obolibrary.org/obo/HP_0002383 |
T7 | 542-562 | Phenotype | denotes | recurrent infections | http://purl.obolibrary.org/obo/HP_0002719 |
T8 | 951-982 | Phenotype | denotes | increased immunoglobulin levels | http://purl.obolibrary.org/obo/HP_0010702 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T141 | 0-39 | Sentence | denotes | 4.2 Intravenous immunoglobulins (IVIG) |
T142 | 41-106 | Sentence | denotes | 4.2.1 Hypothesis: IVIG contains a large pool of human antibodies |
T143 | 107-294 | Sentence | denotes | IVIG is an immunomodulatory treatment currently useful for a variety of human diseases that share an idiopathic origin, ranging from autoimmune disorders to primary antibody deficiencies. |
T144 | 295-603 | Sentence | denotes | Also, IVIG has shown promising results in case of severe (such as sepsis, Parvovirus B19 infection, West Nile virus encephalitis, HIV, Clostridium difficile infections, Mycobacterium avium, Mycobacterium tuberculosis, and Nocardia infections) and recurrent infections in primary antibodies deficiencies [21]. |
T145 | 604-723 | Sentence | denotes | Most patients develop antibodies against the NP and RBD of 2019-nCoV during the second week after infection onset [22]. |
T146 | 724-919 | Sentence | denotes | Analysis of serum samples collected 14 or more days after symptom onset revealed detection of IgG and IgM antibodies against NP in 94% and 88% and RBD in 100% and 94% among patients with COVID19. |
T147 | 920-1045 | Sentence | denotes | Studies consistently show that increased immunoglobulin levels accompany the transition from early to late course of COVID19. |
T148 | 1046-1137 | Sentence | denotes | It poses the possibility that IVIG therapy might help to accelerate recovery from COVID-19. |
T149 | 1139-1221 | Sentence | denotes | 4.2.2 Rationale: IVIG might help to improve the outcome of patients with COVID-19 |
T150 | 1222-1521 | Sentence | denotes | The study [23] included ten patients with COVID-19 who demonstrated worsening symptoms, e.g., decreased lymphocyte count and decreased PaO2/FIO2 ratio and oxygen saturation, following treatment with a short-term moderate-dose corticosteroid (methylprednisolone 80 mg/d) plus immunoglobulin (10 g/d). |
T151 | 1522-1701 | Sentence | denotes | After switching to the double dose of 1600 mg/d methylprednisolone plus 20 g/d immunoglobulin, all of the patients improved in the clinical, laboratory, and paraclinical outcomes. |
T152 | 1702-1833 | Sentence | denotes | Passive immunization protects against disease, and so it should be administered as early as possible when the patient is diagnosed. |
T153 | 1834-2065 | Sentence | denotes | Studies show that the viral RNA of 2019-nCoV reaches its peak during the first week and then gradually decreases and that IgG and IgM begin to rise from the 10th day so that most patients have anti-viral antibodies by the 14th day. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T4 | 240-260 | Phenotype | denotes | autoimmune disorders | http://purl.obolibrary.org/obo/HP_0002960 |
T5 | 361-367 | Phenotype | denotes | sepsis | http://purl.obolibrary.org/obo/HP_0100806 |
T6 | 411-423 | Phenotype | denotes | encephalitis | http://purl.obolibrary.org/obo/HP_0002383 |
T7 | 542-562 | Phenotype | denotes | recurrent infections | http://purl.obolibrary.org/obo/HP_0002719 |
T8 | 951-982 | Phenotype | denotes | increased immunoglobulin levels | http://purl.obolibrary.org/obo/HP_0010702 |