tent with prior reports that SARS-CoV-1 ORF9b suppresses MAVS signaling (Shi et al., 2014). Furthermore, SARS-CoV-2 NSP13 interacts with signaling intermediate TBK1, and NSP15 is associated with RNF41, an activator of TBK1 and IRF3 (Gordon et al., 2020). Simi