Table 2 Clinical Trials Evaluating the Efficacy of IL-6/IL-6R Blockade Therapy
Clinical Trial Intervention
NCT04331795 (COVIDOSE)NCT04320615 (COVACTA)NCT04332913 (TOSCA)NCT04317092 (TOCOVID-19)NCT04335071 (CORON-ACT)NCT04315480ChiCTR2000029765 tocilizumab
NCT04315298 sarilumab
NCT04310228 tocilizumabfavipiravir
NCT04306705 (TACOS) tocilizumabcontinuous renal replacement therapystandard of care
NCT04332094 (TOCOVID) tocilizumabazithromycinhydroxychloroquine
NCT04341870 (CORIMUNO-VIRO) sarilumabazithromycinhydroxychloroquine
NCT0433z638 (COV-AID) tocilizumabsiltuximabanakinrastandard of care