traditional journals, and summarize the current state of science on the fast-evolving field of COVID-19 immunology. We thematically focus on the innate and adaptive immune responses to SARS-CoV-2 and related CoVs, clinical studies and prognostic laboratory correlates, current therapeutic strategies, prospective clinical trials, and vaccine approaches. Innate Immune Sensing of SARS-CoV-2 Innate immune sensing serves