PMC:7200337 / 12674-13118 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T26270","span":{"begin":173,"end":181},"obj":"Body_part"}],"attributes":[{"id":"A89733","pred":"fma_id","subj":"T26270","obj":"http://purl.org/sig/ont/fma/fma84050"}],"text":"L-8 production, potentially by inhibition of NKRF, an endogenous NF-kB repressor (Li et al., 2020a). Collectively, these proinflammatory processes likely contribute to the “cytokine storm” observed in COVID-19 patients and substantiate a role for targeted immunosuppressive treatment regimens. Moving forward, a clear understanding of the delicate balance between antiviral and inflammatory innate immune programs will be essential to developin"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T83","span":{"begin":201,"end":209},"obj":"Disease"}],"attributes":[{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"L-8 production, potentially by inhibition of NKRF, an endogenous NF-kB repressor (Li et al., 2020a). Collectively, these proinflammatory processes likely contribute to the “cytokine storm” observed in COVID-19 patients and substantiate a role for targeted immunosuppressive treatment regimens. Moving forward, a clear understanding of the delicate balance between antiviral and inflammatory innate immune programs will be essential to developin"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T33585","span":{"begin":68,"end":70},"obj":"http://purl.obolibrary.org/obo/CLO_0007074"},{"id":"T27677","span":{"begin":68,"end":70},"obj":"http://purl.obolibrary.org/obo/CLO_0051988"},{"id":"T80865","span":{"begin":82,"end":84},"obj":"http://purl.obolibrary.org/obo/CLO_0001022"},{"id":"T85633","span":{"begin":82,"end":84},"obj":"http://purl.obolibrary.org/obo/CLO_0007314"},{"id":"T17975","span":{"begin":236,"end":237},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T96342","span":{"begin":310,"end":311},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"L-8 production, potentially by inhibition of NKRF, an endogenous NF-kB repressor (Li et al., 2020a). Collectively, these proinflammatory processes likely contribute to the “cytokine storm” observed in COVID-19 patients and substantiate a role for targeted immunosuppressive treatment regimens. Moving forward, a clear understanding of the delicate balance between antiviral and inflammatory innate immune programs will be essential to developin"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T54","span":{"begin":65,"end":67},"obj":"Chemical"},{"id":"T57","span":{"begin":82,"end":84},"obj":"Chemical"},{"id":"T58","span":{"begin":364,"end":373},"obj":"Chemical"}],"attributes":[{"id":"A54","pred":"chebi_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A55","pred":"chebi_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A56","pred":"chebi_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"},{"id":"A57","pred":"chebi_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_30145"},{"id":"A58","pred":"chebi_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"}],"text":"L-8 production, potentially by inhibition of NKRF, an endogenous NF-kB repressor (Li et al., 2020a). Collectively, these proinflammatory processes likely contribute to the “cytokine storm” observed in COVID-19 patients and substantiate a role for targeted immunosuppressive treatment regimens. Moving forward, a clear understanding of the delicate balance between antiviral and inflammatory innate immune programs will be essential to developin"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T9","span":{"begin":173,"end":187},"obj":"Phenotype"}],"attributes":[{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0033041"}],"text":"L-8 production, potentially by inhibition of NKRF, an endogenous NF-kB repressor (Li et al., 2020a). Collectively, these proinflammatory processes likely contribute to the “cytokine storm” observed in COVID-19 patients and substantiate a role for targeted immunosuppressive treatment regimens. Moving forward, a clear understanding of the delicate balance between antiviral and inflammatory innate immune programs will be essential to developin"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T66","span":{"begin":391,"end":404},"obj":"http://purl.obolibrary.org/obo/GO_0045087"}],"text":"L-8 production, potentially by inhibition of NKRF, an endogenous NF-kB repressor (Li et al., 2020a). Collectively, these proinflammatory processes likely contribute to the “cytokine storm” observed in COVID-19 patients and substantiate a role for targeted immunosuppressive treatment regimens. Moving forward, a clear understanding of the delicate balance between antiviral and inflammatory innate immune programs will be essential to developin"}

{"project":"LitCovid-PubTator","denotations":[{"id":"421","span":{"begin":45,"end":49},"obj":"Gene"},{"id":"430","span":{"begin":210,"end":218},"obj":"Species"},{"id":"434","span":{"begin":201,"end":209},"obj":"Disease"}],"attributes":[{"id":"A421","pred":"tao:has_database_id","subj":"421","obj":"Gene:55922"},{"id":"A430","pred":"tao:has_database_id","subj":"430","obj":"Tax:9606"},{"id":"A434","pred":"tao:has_database_id","subj":"434","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"L-8 production, potentially by inhibition of NKRF, an endogenous NF-kB repressor (Li et al., 2020a). Collectively, these proinflammatory processes likely contribute to the “cytokine storm” observed in COVID-19 patients and substantiate a role for targeted immunosuppressive treatment regimens. Moving forward, a clear understanding of the delicate balance between antiviral and inflammatory innate immune programs will be essential to developin"}

{"project":"LitCovid-sentences","denotations":[{"id":"T75","span":{"begin":101,"end":293},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"L-8 production, potentially by inhibition of NKRF, an endogenous NF-kB repressor (Li et al., 2020a). Collectively, these proinflammatory processes likely contribute to the “cytokine storm” observed in COVID-19 patients and substantiate a role for targeted immunosuppressive treatment regimens. Moving forward, a clear understanding of the delicate balance between antiviral and inflammatory innate immune programs will be essential to developin"}