, 95% CI 1.3–2.4; p 0.0002), increased length of ICU stay (mean difference: 2.1, 95% CI 1.2–3.1; p < 0.0001) and increased rate of secondary bacterial or fungal infection (risk ratio: 2.0, 95% CI 1.0–3.8; p 0.04) in patients who received corticosteroids [66]. Question 5 statement So far, no definitive efficacy or effectiveness data are available on the benefit of corti