thods of wet labs [23]. We tried to identify T-cell epitopes that can elicit a robust immune response in the global human population and act as potential vaccine candidates. However, the ability of these epitopes to act as a vaccine candidate needs to be analyzed in Molecular biology lab studies. Our investigation can open new dimensions in crafting peptide-based vaccine regimens for Novel SARS-COV2. The greatest decline in virus expansion was noted following ORF3a removal. ORF7a encodes a 122-amino-acid type I transmembrane protein