Table 1 Parameter estimates for COVID-19 in Guangdong province. Parameter Definitions Esimated value Source β Transmission incidence rate 2.45 × 10−8 Estimated σ The fraction of transmission incidence rate for exposed individuals 0.63 Estimated α Disease-induced death rate 0.00375 Estimated ν Transmission rate of exposed individuals to the infected class 0.183 [Zhao et al., 2020a], [Zhao et al., 2020b] γ(t) Recovery rate 0.008+0.19(1+e5.0126−0.1846t) Estimated q1(t) Quarantined rate of susceptible individuals 0.28 Estimated q2(t) Quarantined rate of exposed individuals 0.76 Estimated q3 Quarantined rate of infected individuals 0.89 Estimated A(t) Input number 86926 data B1 Output number 21356 data p1 The fraction of input population into susceptible class 0.9999927 Computed p2 The fraction of input population into exposed class 0.0000073 Computed p3 The fraction of input population into infected class 0 Assumed Initial values Definitions Esimated value Source N(0) Initial total population 113460000 GSY S(0) Initial susceptible population 113346174 Estimated E(0) Initial exposed population 31 Estimated I(0) Initial infected population 19 Estimated Sq(0) Initial quarantined susceptible population 113460 Estimated Eq(0) Initial quarantined exposed population 128 data Iq(0) Initial quarantined infected population 184 data R(0 Initial recovered population 4 data Note: GSY: Guangdong Statistical Yearbook, 2019.