48 26 56 28 Age (years, mean ± SD) 74.8 ± 16.8 59.2 ± 10.3 <0.0001 74.0 ± 12.6∗ 67.8 ± 10.8# <0.0001 Male gender (n, %) 25 (52.1) 15 (57.7) 0.807 27 (48.2)∗ 25 (